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Cell Biology / Development (composition) PhD Projects, Programs & Scholarships

We have 18 Cell Biology / Development (composition) PhD Projects, Programs & Scholarships

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We have 18 Cell Biology / Development (composition) PhD Projects, Programs & Scholarships

MSc by Research programme - Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus

Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more

Epigenetic regulation of meiotic genes by the transcription factor Hac1i

A self-funded PhD studentship to investigate how the transcription factor Hac1i achieves epigenetic regulation of early meiotic genes is available in the group of Dr. Read more

Mass spectrometry analysis of eIF2B bodies during stress and disease

One of the biggest challenges for cells is responding to their ever-changing environment. Cells overcome stress by activating stress-responsive signalling pathways such as the ‘integrated stress response’ (ISR). Read more

Multimodal bioimaging of viral replication organelles and inclusion bodies

This project will compare two important viral pathogens of livestock using a multi-layered approach combining state-of-the-art bioimaging to generate ultrastructural insights into how inclusion bodies (IBs) and replication organelles (ROs) – sites of cellular reorganisation used for RNA virus replication - form and function. Read more

The role of Myh10 (Non-Muscle Myosin IIB) in epicardial-myocardial cross talk during coronary vessel development.

During cardiac development the coronary vessels form from the epicardium, which is the outer epithelial cell layer of the heart. Formation of the coronary vasculature is a critical event in cardiac development, since the vasculature is required to nourish the cardiac muscle and maintain cardiac function throughout life. Read more

Extracellular matrix remodeling in neuromuscular synapse development

Motor neurons, skeletal muscles, and perisynaptic Schwann cells interact with extracellular matrix (ECM) to form the tetrapartite synapse in the peripheral nervous system. Read more

Chemical probes for the study of carbohydrate-active enzymes

Background. Carbohydrates play many roles in cells from all kingdoms of life. In addition to their well-known role as an energy source, they also have important functions in, for example, communication between cells, cell-pathogen interactions, intracellular signalling, and maintaining a stable cellular environment. Read more

The role of tetraspanin proteins in the regulation of the tumour microenvironment.

The immune cell landscape within tumour microenvironment is controlled by an elaborate network of communications involving chemokines, cytokines and growth factors which are produced by tumour-infiltrating immune cells themselves, by cancer cells and by other cell types in cancerous tissues (e.g. Read more

Developing Novel Therapies to Prevent Atherosclerosis

Background. There is intense interest in identifying the genes that predispose to the development of atherosclerosis. We recently carried out an expression analysis of human tissue using microarrays that identified several candidate genes. Read more

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