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Cell Biology / Development (critical care) PhD Projects, Programs & Scholarships

We have 21 Cell Biology / Development (critical care) PhD Projects, Programs & Scholarships

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  The Impact Of Haemodynamics Generated In Mechanical Circulatory Support Devices On Primary Haemostasis Using A Blood-Shearing Device
  Dr J Pauls
Applications accepted all year round

Funding Type

PhD Type

The Critical Care Research Group (CCRG), based at the The Prince Charles Hospital (TPCH) in Brisbane, Australia, is seeking highly motivated, skilled and committed PhD candidates to join our multidisciplinary and international research team to commence a PhD project.
  Fueling chemotherapy resistance in triple-negative breast cancer
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

Triple-negative breast cancer (TNBC) is a molecularly heterogeneous group of diseases defined by the lack of estrogen receptor (ER), progesterone receptor (PR) and absence of human epidermal growth factor receptor-2 (HER2) amplification.
  Mechanisms of regulating gene expression via selective mRNA transport
  Dr V Wickramasinghe, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

A critical step in the gene expression pathway that is altered in cancer is nuclear export of mRNA. We have demonstrated that mRNA export is not constitutive, but highly selective and can regulate distinct biological processes through poorly understood mechanisms.
  Unravelling the oncogenic activities of serum- and glucocorticoid-regulated kinase 1 (SGK1)
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

The phosphoinositide 3-kinase (PI3K) pathway is a master regulator of numerous cellular phenotypes associated with cancer including cell survival, proliferation, growth, altered metabolism and malignant transformation.
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  Molecular and cell-biological mechanisms mediating establishment of neuron polarity during development
  Dr R Das, Dr C Francavilla
Applications accepted all year round

Funding Type

PhD Type

Background. Cells undergoing neuronal differentiation in the embryonic spinal cord delaminate from the neuroepithelium, resulting in loss of apical cell polarity.
  Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism
  Dr D Bechtold, Prof D Ray
Applications accepted all year round

Funding Type

PhD Type

24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g.
  Dissecting the molecular mechanisms of neural-fibroblast interactions in woundhealing
  Dr D Lambert, Prof F M Boissonade, Dr A Nikolaev
Application Deadline: 31 March 2020

Funding Type

PhD Type

The skin and other epithelial surfaces, such as the oral mucosa, play a critical role as a. barrier to viral and bacterial pathogens and other environmental insults.
  Modulation of platelet-mediated innate immune responses in chronic lymphocytic leukaemia
  Dr M Arman
Application Deadline: 31 March 2020

Funding Type

PhD Type

Chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia in the Western World. B-cell receptor-induced intracellular signals are critical for the survival of leukaemia cells and disruption of this pathway by the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib is a highly effective CLL therapy.
  Re-purposing diabetes medicines to manage bleeding complications in myeloproliferative neoplasms.
  Prof Tim Palmer, Dr D Allsup
Application Deadline: 31 March 2020

Funding Type

PhD Type

Myeloproliferative neoplasms (MPNs) are a group of three related blood cancers in which the bone marrow overproduces one of the three cellular components of blood (erythrocytes, leukocytes and platelets).
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  Epigenetic mechanisms of behavioural, placental and cognitive impairment in a neurodevelopmental model for schizophrenia
  Dr R Hager, Prof J Neill, Dr J Glazier
Applications accepted all year round

Funding Type

PhD Type

A fundamental question in disease research is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016).
  The functions of the Class II Pi3-kinase signals in vivo
  Dr L MacDougall, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Phosphoinositide lipids (PIPs) play critical roles in development and the homeostasis of adult tissues and their dysfunction has been linked to major human diseases such as cancer, diabetes, myopathies and neuropathies.
  The role of cell adhesion proteins in healthy and cancerous epithelial cells
  Dr C Ballestrem, Prof D R Garrod
Applications accepted all year round

Funding Type

PhD Type

The cells’ ability to properly communicate with its environment is fundamental for the healthy development of individual organisms.
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