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We have 148 Cell Biology (culture) PhD Projects, Programmes & Scholarships

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Cell Biology (culture) PhD Projects, Programmes & Scholarships

We have 148 Cell Biology (culture) PhD Projects, Programmes & Scholarships

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MScR - Preserving t-tubule function in adult cardiac myocytes in short-term culture

University of Bristol School of Physiology, Pharmacology & Neuroscience
Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more
 Supervisors: Prof A James, Dr S Harmer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bioengineering a dynamic culture platform to improve the maturity of iPSC-derived muscle organoids

Murdoch Childrens Research Institute Stem Cell Biology
About the project. Heart disease is a critical health burden and leading cause of mortality worldwide. To understand disease mechanisms and develop future treatments for heart disease, we have developed a human cardiac organoid platform derived from pluripotent stem cells. Read more
 Supervisors: Dr H Voges, Assoc Prof RM Mills
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Vascularising human mini-brains in a dish

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Blood vessels play a pivotal role in brain development and function. They promote tissue growth and survival by supplying nutrients and oxygen to surrounding tissues, signals to progenitor populations, as well as guiding neuronal migration. Read more
 Supervisors: Dr PA Alexandre, Prof D Long
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more
 Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Elucidation of a new pathological mechanism for brittle bone disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Diagnostics for FMF patients and carrier survival in pandemics

The University of Manchester Faculty of Biology, Medicine and Health
Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more
 Supervisors: Dr P Arkwright, Dr G Lopez-Castejon, Dr J Cavet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: Assessing health benefits of gut microbiota using host-microbe interaction models of the human gut

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Dr S Gratz, Prof K Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of myocardial ischemic adaptation in the presence of comorbidity factors on in vitro cell culture models

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy
Metabolic derangements, such as obesity or diabetes, are major risk factors of cardiovascular diseases. Read more
 Supervisor: Dr A Görbe
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

University of Dundee School of Medicine
Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more
 Supervisor: Dr M Mclean
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Sensitizing AML cells to RAR and VDR ligands (vitamin A and D derivatives) to prevent leukaemia relapse

Medical University of Vienna Institute for Pathophysiologie and Allergy
The doctoral candidate (DC) will perform basic research on leukaemia cell biology in vitro and in vivo at the Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel. Read more
 Supervisor: Dr MD Danilenko
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

University of Greenwich School of Pharmacy (Medway Campus)
Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more
 Supervisor: Dr S Ashraf
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School
Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more
 Supervisor: Dr P Maghsoudlou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health
The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more
 Supervisors: Dr G Mavria, Dr S Bell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

King’s College London School of Cancer and Pharmaceutical Sciences
Talented and motivated students, passionate about doing research and advancing cancer research, are invited to apply for this PhD position. Read more
 Supervisor: Dr H Sailem
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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