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We have 47 Cell Biology (equality) PhD Projects, Programmes & Scholarships

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Cell Biology (equality) PhD Projects, Programmes & Scholarships

We have 47 Cell Biology (equality) PhD Projects, Programmes & Scholarships

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Investigating WSB-1 as a prognostic marker and therapeutic target in urogenital cancers

The University of Manchester Faculty of Biology, Medicine and Health
Prostate cancer (PCa) is the commonest cancer diagnosed in men, with 5-year survival rates of 60% in those with advanced disease. Read more
 Supervisors: Dr IP Monteiro dos Santos Pires, Prof AC Choudhury
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Control of gene expression in embryonic development

The University of Manchester Faculty of Biology, Medicine and Health
The impressive range of anatomical variations observed in animals along their body axis is the result of distinct control mechanisms governing gene expression. Read more
 Supervisors: Prof N Bobola, Dr M Birket
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating immune contributions to frontotemporal dementia and motor neuron disease

The University of Manchester Faculty of Biology, Medicine and Health
Frontotemporal dementia (FTD) is the 2nd most common form of dementia affecting younger people, with a typical age of onset in the mid-late 50s. Read more
 Supervisors: Dr SR Ryan, Prof D Brough
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Characterisation of how pro-peptide regions of collagen control extracellular matrix homeostasis, in health and musculoskeletal diseases

The University of Manchester Faculty of Biology, Medicine and Health
Collagen-I (‘collagen’ from hereon) is the most abundant protein in the human body (circa 25% of total protein mass), providing structure to organs with very different functions (e.g. Read more
 Supervisors: Dr JC Chang, Dr TZ Zacharchenko, Prof C Baldock
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying critical pathways regulating autoimmunity in immuno-oncology and arthritis patients. Short title: IPADS (Immune PAthways for Drug Side-effects)

The University of Manchester Faculty of Biology, Medicine and Health
Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more
 Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of nuclear localisation of adhesion proteins in tumour growth and invasion

The University of Manchester Faculty of Biology, Medicine and Health
Overview. This project seeks to understand how tumour growth and invasion are controlled by the localisation of certain proteins in cancer cells. Read more
 Supervisors: Dr AB Byron, Dr K Finegan, Dr C Tournier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Nitrate supplementation in pregnancy: maternal, fetal and offspring outcomes

The University of Manchester Faculty of Biology, Medicine and Health
Maternal diet has a significant impact on fetal growth and development, as well as pregnancy outcomes and long-term offspring health. Dietary patterns… Read more
 Supervisors: Dr E Cottrell, Dr M Dilworth
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Chaperones and the response to protein misfolding stress

The University of Manchester Faculty of Biology, Medicine and Health
Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more
 Supervisors: Prof C M Grant, Prof M Ashe
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the interaction of La related proteins with colliding ribosomes

The University of Manchester Faculty of Biology, Medicine and Health
Translation of mRNA into proteins is a critical cellular biological process for all life. This requires ribosomes to act with an array of translation factors to decode mRNA sequences. Read more
 Supervisors: Prof G D Pavitt, Dr A Roseman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Graphene oxide as growth factor carriers for meniscus tissue engineering

The University of Manchester Faculty of Biology, Medicine and Health
Damage to the meniscus of the knee leads to increased risk of osteoarthritis. Tissue engineering of a healthy meniscal fibrocartilage offers the opportunity to restore function. Read more
 Supervisors: Dr H Lu, Dr S Richardson, Prof P Xiao
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identification of transcriptomic signatures of autism-like neurodevelopmental disorder

The University of Manchester Faculty of Biology, Medicine and Health
The overarching aim of this project is to define transcriptional patterns and identify new genetic elements essential for the correct development of the human brain. Read more
 Supervisors: Dr PG Grzechnik, Dr A J Whitmarsh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Determining how immune responses are regulated in the lung and gut by the local environment

The University of Manchester Faculty of Biology, Medicine and Health
The immune system must respond quickly to infection but must also be tightly regulated so it ignores harmless substances and our own tissues. Read more
 Supervisors: Prof M Travis, Prof R K Grencis, Prof D Thornton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Circadian mechanisms in psoriasis: therapeutic opportunities

The University of Manchester Faculty of Biology, Medicine and Health
Hallmark features of psoriasis symptoms vary through time, suggesting an important role for circadian circuits in driving disease expression, and offering the potential of chronotherapy. Read more
 Supervisors: Dr H Young, Dr I Iqbal, Prof D Ray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating monogenic disorders of the protein synthesis machinery

The University of Manchester Faculty of Biology, Medicine and Health
Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more
 Supervisors: Dr P Kasher, Dr S Banka, Prof G D Pavitt
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cell signalling and gene expression dynamics in Drosophila

The University of Manchester Faculty of Biology, Medicine and Health
During Drosophila development, cell signalling and gene expression are regulated in space and time to allow the correct cell fate decisions. Read more
 Supervisor: Prof H Ashe
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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