Cell Biology (induced pluripotent stem cells) PhD Projects, Programmes & Scholarships

We have 16 Cell Biology (induced pluripotent stem cells) PhD Projects, Programmes & Scholarships

Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School

Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more

Supervisor: Dr P Maghsoudlou

Year round applications PhD Research Project Self-Funded PhD Students Only

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Optogenetic sculpting of next-generation organoids for disease modelling of congenital malformations including spina bifida

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

The ability to generate human induced pluripotent stem cells (iPSC) from adult cell types has revolutionised regenerative medicine research. Read more

Supervisors: Dr G Galea, Prof J Sowden

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Effects of FADS2 single-nucleotide polymorphisms on clathrin-mediated endocytosis in human induced pluripotent stem cell-derived neurons

Cardiff University Cardiff School of Medicine

Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more

Supervisor: Prof A Harwood

7 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology

The 46th chromosome in XX female mammals, the second X, has to be switched off. That way females equalize gene dosage of X-linked genes with XY males. Read more

Supervisors: Dr Y Markaki, Prof J Schwabe, Dr JH Hodgkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD in stem cell modelling for neuropsychiatric disorders

University of Melbourne Anatomy and Physiology

This project provides a unique opportunity to explore the developmental origins of schizophrenia—a severe mental health disorder—using cutting-edge patient-derived stem cell models. Read more

Supervisor: Dr M Di Biase

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Vascularising human mini-brains in a dish

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Blood vessels play a pivotal role in brain development and function. They promote tissue growth and survival by supplying nutrients and oxygen to surrounding tissues, signals to progenitor populations, as well as guiding neuronal migration. Read more

Supervisors: Dr PA Alexandre, Prof D Long

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Identification of transcriptomic signatures of autism-like neurodevelopmental disorder

The University of Manchester Faculty of Biology, Medicine and Health

The overarching aim of this project is to define transcriptional patterns and identify new genetic elements essential for the correct development of the human brain. Read more

Supervisors: Dr PG Grzechnik, Dr A J Whitmarsh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Leveraging Functional Genomics to Understand Mitonuclear Combinations in Leber Hereditary Optic Neuropathy (Ref: FFS24/HLS/APP/WINTER)

Northumbria University Faculty of Health and Life Sciences

Mitochondria are small structures present in every cell of our body, which convert the food we eat into an energy source that cells can use. Read more

Supervisors: Dr M Winter, Prof M Lako, Dr G Hilgen

25 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

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Human Genetics, Genomics and Disease: Sequence determinants of mRNA fate in neuronal differentiation

University of Edinburgh College of Medicine and Veterinary Medicine

Research Group: MRC Human Genetics Unit

Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center Berlin Institute for Medical Systems Biology, Berlin, Germany. Read more

Supervisor: Dr G Kudla

19 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

ADCY5-related disease is a genetic disorder caused by mutations in the ADCY5 gene, which encodes for the isoform 5 of adenylyl cyclase (ADCY5)1. Read more

Supervisors: Dr S Barral, Dr M Kurian, Dr HZ Zhou

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Investigating the metabolic link between leukaemia and heart failure (RUSHWORTHS_U24BIGC)

University of East Anglia Norwich Medical School

Primary supervisor - Dr Stuart Rushworth. Secondary supervisor - Dr James Smith. Rushworth Lab. This 4-year PhD project funded by the Big C cancer charity represents an exciting opportunity to develop and conduct research at the forefront of cancer research. Read more

Supervisor: Dr S Rushworth

7 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Bioengineering a dynamic culture platform to improve the maturity of iPSC-derived muscle organoids

Murdoch Childrens Research Institute Stem Cell Biology

About the project. Heart disease is a critical health burden and leading cause of mortality worldwide. To understand disease mechanisms and develop future treatments for heart disease, we have developed a human cardiac organoid platform derived from pluripotent stem cells. Read more

Supervisors: Dr H Voges, Assoc Prof RM Mills

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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MSc by Research: Function of presomitic mesoderm specific phosphorylation of the Notch intracellular domain in somitogenesis

University of Dundee School of Life Sciences

The Notch signalling pathway is one of the key pathways required for the developing embryo. It is especially important for the process of somitogenesis, the formation of body segments that develop into e.g. Read more

Supervisor: Prof J K Dale

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 16 Cell Biology (induced pluripotent stem cells) PhD Projects, Programmes & Scholarships

Cell Biology (induced pluripotent stem cells) PhD Projects, Programmes & Scholarships

We have 16 Cell Biology (induced pluripotent stem cells) PhD Projects, Programmes & Scholarships

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