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Cell Biology / Development (medicinal) PhD Projects, Programs & Scholarships

We have 9 Cell Biology / Development (medicinal) PhD Projects, Programs & Scholarships

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  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
  Dr I Dreveny
Applications accepted all year round

Funding Type

PhD Type

Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
  Efficacy testing of biomaterial delivered iPS cells in in vitro cultures systems to mimic the degenerate niche
  Prof C Le Maitre, Prof C Sammon
Application Deadline: 31 May 2019

Funding Type

PhD Type

Low back pain (LBP) is a leading cause of disability and morbidity worldwide. It is widely accepted that a major contributor to LBP is intervertebral disc degeneration (IDD).
  New Dimensions in Cannabinoid Receptor 2 Therapeutic Development: Exploring Spatial and Temporal Signalling Bias
  Dr N Grimsey
Applications accepted all year round

Funding Type

PhD Type

Compounds derived from Cannabis sativa, termed “cannabinoids”, primarily exert their effects via two G protein-coupled receptors (GPCRs), Cannabinoid Receptors 1 and 2 (CB1 and CB2).
  Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs).
  Polysialyltransferases as a target in metastatic cancer
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases.
  Targeting the P2X7 purinergic receptor in melanoma (STOKESLU19SF)
  Dr L Stokes, Dr C Morris
Application Deadline: 31 May 2019

Funding Type

PhD Type

There is much research into trying to regain control of cell proliferation or cell death (apoptosis) in cancer. Different strategies exist to do this and a multitude of individual receptor targets are being identified in tumour cell lines and primary cells.
  Small Molecule Signalling in Stem Cell Differentiation
  Dr D France
Applications accepted all year round

Funding Type

PhD Type

Use of stem cells has the potential to transform regenerative medicine, if appropriate strategies can be identified for the controlled differentiation of these progenitors.
  Pre-clinical testing of new therapeutic treatments for cystic kidney disease
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

The primary cilium on the ventral surface of most vertebrate cells acts as an “antennae” that receives and transduces chemo- and mechanosensory signals.
  CRISPR-Cas9 genome editing and super-resolved live cell imaging to study the extracellular microenvironment at the single molecule level
  Dr A Piccinini, Prof D Heery
Applications accepted all year round

Funding Type

PhD Type

The three-dimensional space around and between mammalian cells is filled with a complex network of extracellular matrix (ECM) molecules, which instruct fundamental processes such as cell survival, differentiation and migration, in addition to providing structural support for cells.
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