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We have 4 Cell Biology (mmp) PhD Projects, Programmes & Scholarships

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Cell Biology (mmp) PhD Projects, Programmes & Scholarships

We have 4 Cell Biology (mmp) PhD Projects, Programmes & Scholarships

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Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

University of Bristol Bristol Medical School
Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more
 Supervisor: Prof S Satchell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences
Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more
 Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy
Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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