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Cell Biology / Development (monoclonal antibodies) PhD Projects, Programs & Scholarships

We have 7 Cell Biology / Development (monoclonal antibodies) PhD Projects, Programs & Scholarships

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  Bispecific monoclonal antibodies for cancer immunotherapy
  Prof W Bodmer, Prof P McHugh
Application Deadline: 10 January 2020

Funding Type

PhD Type

THE PROJECT. Monoclonal antibodies (MCAs) are now widely used for cancer therapy. DNA recombinant technology enables the production of MCAs that target cancer specific determinants and immune cells, attracting them to the cancer cells and so killing them.
  Chimeric Antigen B Cell (CAR B Cell) Therapy for Targeted Therapeutic and Prophylactic Vaccination
  Prof L Seymour, Prof S Draper
Application Deadline: 10 January 2020

Funding Type

PhD Type

Lead supervisor. Prof Len Seymour, Department of Oncology, University of Oxford. Co-supervisor. Prof Simon Draper, Jenner Institute, University of Oxford.
  Antibody-drug conjugates (ADCs) for the treatment of solid tumours
  Dr S Karagiannis, Prof J Downward
Application Deadline: 29 November 2019

Funding Type

PhD Type

An Antibody-Drug Conjugate (ADC) comprises an antibody targeted toward a tumour cell surface antigen, coupled through a chemical linker to a highly-cytotoxic drug.
  (BBSRC DTP) Development of anti-cancer agents and biomarkers that target intrinsically disordered regions of transcription factors and protein kinases
  Prof J Waltho, Dr A Almond
Application Deadline: 31 January 2020

Funding Type

PhD Type

The controlled manipulation of transcription factors, protein kinases and protein phosphatases is central to improving our understanding of cellular processes and, importantly, in the development of next-generation therapeutics for a variety of cancers.
  (BBSRC DTP) Developing a whipworm vaccine composed of virus-like particles expressing Trichuris T cell epitopes
  Prof K Else, Prof J P Derrick
Application Deadline: 31 January 2020

Funding Type

PhD Type

Vaccination is one of the greatest advances in global health; however most successful vaccines have been made empirically. We still have little insight into how many vaccines work and the mechanisms by which they trigger protective immune responses.
  Tetraspanin structure and function
  Dr L J Partridge
Applications accepted all year round

Funding Type

PhD Type

The tetraspanins are a diverse, conserved family of eukaryotic membrane proteins. Their principal feature is the ability to form dynamic multi-molecular assemblies in cell membranes known as tetraspanin enriched microdomains (TEM).
  Autoreactive B cells in Sjögren’s syndrome #202014
  Prof L Dustin, Prof C Buckley
Application Deadline: 10 January 2020

Funding Type

PhD Type

Primary Supervisor. Lynn B Dustin, PhD. Secondary Supervisor. Christopher D Buckley DPhil, FRCP. Sjögren’s syndrome (SS) is the second most common rheumatic disease after rheumatoid arthritis and can also arise as a complication of other autoimmune diseases.
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