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We have 32 Cell Biology (proteomic) PhD Projects, Programmes & Scholarships

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Cell Biology (proteomic) PhD Projects, Programmes & Scholarships

We have 32 Cell Biology (proteomic) PhD Projects, Programmes & Scholarships

Diagnostics for FMF patients and carrier survival in pandemics

Background. Familial Mediterranean Fever (FMF) is a rare inherited genetic disease where patients acquire a mutation on the pyrin gene leading to excessive inflammasome activation and excessive inflammation. Read more

Biological pathways supporting the formation and function of chromatin (Scholarship)

Every cell in our body contains the same DNA yet each cell expresses a different set of genes. These changes in gene expression are heavily influenced by histone proteins, their role in packaging DNA into chromatin and the “epigenetic” information they carry. Read more

ERK5 MAPK signalling in Alzheimer’s disease

  Research Group: Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more

MSc by Research: Molecular characterisation of the factors driving lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function.  At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

MSc by Research: How are SUMO substrates selected for modification ?

SUMO has diverse roles in cellular physiology that in most cases are mediated by its ability to interact non-covalently with hydrophobic patches of low sequence complexity known as SUMO Interaction Motifs (SIMs). Read more

Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder

Tousled-like kinase 2 (TLK2) was recently identified as a novel genetic locus for a neurodevelopmental disorder. Patients predominantly possess de novo mutations in TLK2, leading to a reduction in its expression or kinase activity. Read more

Driving phenotypic plasticity and metastasis in small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Underlying this aggressiveness is intra-tumoural heterogeneity driven by phenotypic plasticity wherein tumour cells transition from a neuroendocrine (NE) to a non-neuroendocrine (non-NE) phenotype. Read more

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