Cell Biology (stress) PhD Projects, Programmes & Scholarships

We have 42 Cell Biology (stress) PhD Projects, Programmes & Scholarships

Chaperones and the response to protein misfolding stress

The University of Manchester Faculty of Biology, Medicine and Health

Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more

Supervisors: Prof C M Grant, Prof M Ashe

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification of phosphatases that inactivate the endoplasmic reticulum stress sensor Ire1

Durham University Department of Biosciences

A self-funded PhD studentship is available in the group of Dr. Martin Schröder in the Department of Biosciences at Durham University to study stress signalling mechanisms originating from the endoplasmic reticulum. Read more

Supervisor: Dr M Schroeder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring tyrosine metabolism as a source of oxidative stress

University of Liverpool Institute of Life Course and Medical Sciences

We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress associated with tyrosine metabolism. Read more

Supervisors: Dr BN Norman, Dr JH Hughes, Prof L Ranganath

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Exploring the roles of a novel prion-like protein in stress resistance and ageing (TAYLOR_U24DTP2)

University of East Anglia School of Biological Sciences

Primary Supervisor: Dr. Rebecca Taylor . Secondary Supervisor: Prof. Tom Wileman (QIB) . Ageing is associated with increased rates of disease, including neurodegenerative conditions. Read more

Supervisor: Dr R Taylor

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Unravelling the Intricacies of Stress Hormone Regulation

University of Reading Department of Biomedical Sciences

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Supervisor: Dr A B Bicknell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more

Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of oxidative metabolites in joint destruction in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress in alkaptonuria (AKU) and associated conditions. Read more

Supervisors: Dr BN Norman, Dr JH Hughes, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating the impact of genotoxic aldehyde stress in premature ageing

University of Leicester Department of Chemistry

Aldehydes are highly reactive chemicals that are common pollutants and human metabolites. However, the vast majority of aldehydes’ biological functions are unknown. Read more

Supervisors: Dr R Hopkinson, Dr K Tanaka

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Protecting cells from mechanical stress: A novel role of cell-surface receptor LRP1 in extracellular matrix- nuclei communication.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Cellular adaptation to mechanical strain (mechano-adaptation) is increasingly understood to be conferred by Lamin intermediate filament proteins located within the nuclear lamina. Read more

Supervisor: Dr K Yamamoto

Year round applications PhD Research Project Self-Funded PhD Students Only

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Stress hormone metabolism – a novel anti-fibrotic therapeutic pathway for chronic wounds (Ref SHLS24121)

Glasgow Caledonian University School of Health and Life Sciences

We have an exciting PhD opportunity within the Molecular Mechanisms of Long-term Conditions research group at Glasgow Caledonian University (https://www.gcu.ac.uk/aboutgcu/academicschools/hls/research/researchgroups/molecularmechanismsoflongtermconditions) to join the laboratory of Dr Catherine Wright with a supervisory team based in GCU and the University of Leeds. Read more

Supervisors: Dr C Wright, Dr S Patterson, Dr B Alcacer-Pitarch

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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MSc by Research: Degrade or die: Understanding proteasome regulation upon stress

University of Dundee School of Life Sciences

The Rousseau lab is interested in decoding how protein degradation by the proteasome is regulated in cells so that accumulation of unfolded, misfolded, or damaged proteins can be cleared before they become deleterious. Read more

Supervisor: Dr A Rousseau

Year round applications PhD Research Project Self-Funded PhD Students Only

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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more

Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

The University of Manchester Faculty of Biology, Medicine and Health

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

Supervisors: Dr HS Shokr, Dr CT Tapeinos, Dr H Aojula

Year round applications PhD Research Project Self-Funded PhD Students Only

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The BCAT1 CXXC Motif and Oncogenesis in Acute Myeloid Leukaemia

University of Worcester Research School

The BCAT1 gene is implicated in the pathogenesis of many cancer types, including acute myeloid leukaemia (AML)1–4. Recently, our group identified a novel antioxidant role for BCAT1 in AML cells5. Read more

Supervisor: Dr S Coles

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of Aquaporins in age related diseases

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more

Supervisor: Dr C Staunton

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 42 Cell Biology (stress) PhD Projects, Programmes & Scholarships

Cell Biology (stress) PhD Projects, Programmes & Scholarships

We have 42 Cell Biology (stress) PhD Projects, Programmes & Scholarships

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