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Cell Biology / Development (yeast) PhD Projects, Programs & Scholarships

We have 29 Cell Biology / Development (yeast) PhD Projects, Programs & Scholarships

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  (BBSRC DTP) Tackling the genomic dark matter through system engineering of ncRNAs in yeast
  Prof D Delneri, Prof P Cai
Application Deadline: 31 January 2020

Funding Type

PhD Type

Non-coding RNAs (ncRNAs) are thought as of genomic "dark matter" for which the biological significance has been largely underestimated.
  Engineering synthetic ribosomal RNAs (rRNAs) in yeast
  Prof P Cai, Prof D Delneri
Applications accepted all year round

Funding Type

PhD Type

Advances in DNA synthesis technology have led to rapid growth in the field of synthetic biology, heralding a nascent era of synthetic genomics.
  Engineering tRNA neochromosomes in yeast
  Prof P Cai, Prof D Delneri
Applications accepted all year round

Funding Type

PhD Type

Advances in DNA synthesis technology have led to rapid growth in the field of synthetic biology, heralding a nascent era of synthetic genomics.
  The role mRNA-specific translation during chronological aging
  Prof C M Grant, Prof M Ashe, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Biological ageing can be thought of as a progressive decline in the ability of an organism to survive stress and disease. It is a complex process which is influenced by both genetic and environmental factors.
  EASTBIO: Does Rif1 regulate meiotic DNA replication and recombination?
  Dr A Lorenz, Prof A Donaldson, Prof A Marston
Application Deadline: 5 January 2020

Funding Type

PhD Type

Supervisors. Dr Alexander Lorenz (University of Aberdeen). https://homepages.abdn.ac.uk/a.lorenz/pages/index.html. Professor Anne Donaldson (University of Aberdeen).
  Cell polarity regulation in a model eukaryote
  Research Group: Institute of Cell Biology
  Prof K E Sawin
Application Deadline: 5 January 2020

Funding Type

PhD Type

Normal cell architecture and organisation depends on internal and external cues and landmarks. Upon stress, cell organisation can also change in a coordinated way, either to generate changes in shape or to achieve homeostasis at the level of the entire cell.
  Interplay between the translation of upstream open reading frames and ribosome nascent chain-associated factors to control gene expression in eukaryotic cells
  Dr M Pool, Prof G D Pavitt
Applications accepted all year round

Funding Type

PhD Type

Eukaryotic mRNAs typically contain one open reading frame that is translated into protein. However many mRNAs contain additional upstream ORFs (uORFs) that regulate protein expression by controlling the flow of ribosomes to the main ORF, often by regulated reinitiation.
  Understanding the role that the RNA helicase UPF1 plays in sorting ribonucleoprotein (RNP) complexes and the mechanism by which this role of UPF1 might reduce cellular stress and cell degeneration.
  Research Group: BBSRC MIBTP
  Dr S Brogna
Application Deadline: 7 January 2020

Funding Type

PhD Type

This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
  EASTBIO The RNA-bound proteome
  Research Group: Institute of Cell Biology
  Prof D Tollervey
Application Deadline: 5 January 2020

Funding Type

PhD Type

Second Supervisor. Angus Lamond University of Dundee. Functional interactions between RNAs and proteins underpin gene expression and defects in RNA-protein interactions form the basis of numerous human diseases.
  Epigenetic regulation of meiotic genes by the transcription factor Hac1i
  Dr M Schroeder
Applications accepted all year round

Funding Type

PhD Type

A self-funded PhD studentship to investigate how the transcription factor Hac1i achieves epigenetic regulation of early meiotic genes is available in the group of Dr.
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