Cell Biology (innate) PhD Projects, Programmes & Scholarships

We have 15 Cell Biology (innate) PhD Projects, Programmes & Scholarships

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Supervisor: Dr M Soller

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Using a zebrafish tumour initiation model, single cell transcriptomics and in vivo live imaging to dissect mechanisms driving the development of tumour promoting neutrophils from the inception of cancer.

University of Edinburgh College of Medicine and Veterinary Medicine

Research Group: Edinburgh Cancer Research Centre

****Please direct any enquires to Dr Yi Feng - yi.feng@ed.ac.uk in the first instance****. Students will be registered for their degree at either the University of Glasgow or Edinburgh, depending on the project they apply for. Read more

Supervisors: Dr A Khamseh, Dr L Carlin, Dr X Fu, Dr Y Feng

20 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Ejecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion

University of York York Biomedical Research Institute

Background. The epithelial tissues of our bodies use physical barriers and innate defences to fight viral infection. Read more

Supervisor: Dr S Baker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences

Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more

Supervisors: Dr HL Wright, Prof MJ Peffers

Year round applications PhD Research Project Self-Funded PhD Students Only

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Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School

Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more

Supervisor: Dr P Maghsoudlou

Year round applications PhD Research Project Self-Funded PhD Students Only

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Defining the mechanistic basis of Aspergillus fumigatus and Non-tuberculous mycobacteria coinfection

The University of Manchester Faculty of Biology, Medicine and Health

Respiratory infections caused by bacteria, fungi and viruses are a global cause of death according to the WHO. Respiratory coinfections are on the rise and in general linked with poor patient outcomes. Read more

Supervisors: Dr S Gago, Dr CK Kosmidis, Prof L Tabernero

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more

Supervisors: Dr F Errington-Mais, Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences

Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more

Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner

Year round applications PhD Research Project Self-Funded PhD Students Only

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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Regulation of microglial phenotypes by adenosine and in contribution to ageing in the brain

University of Dundee School of Life Sciences

Microglia are the major innate immune cells in the central nervous system and are required for the response to invading pathogens, removal of damaged or… Read more

Supervisors: Prof S Arthur, Dr A Lloyd

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Mapping the host response to fungal pathogens

University of Dundee School of Life Sciences

Fungal pathogens represent a significant clinical problem for which treatment options remain limited. Read more

Supervisor: Prof S Arthur

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular Mechanisms of Resolution of Inflammation

University of Birmingham Institute of Inflammation and Ageing

We are seeking talented, motivated students to join the research group led by Professor Andy Clark (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/clark-andy.aspx), a member of the University of Birmingham’s Rheumatology Research Group (https://www.birmingham.ac.uk/research/inflammation-ageing/research/rheumatology-research-group/index.aspx). Read more

Supervisor: Prof A Clark

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification of the molecular pathways that guide tissue regeneration

University of Sheffield School of Biosciences

The study of regenerative biology aims to elucidate the innate ability of organisms to replace tissues or organs after they have been removed or damaged. Read more

Supervisor: Dr H Roehl

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 15 Cell Biology (innate) PhD Projects, Programmes & Scholarships

Cell Biology (innate) PhD Projects, Programmes & Scholarships

We have 15 Cell Biology (innate) PhD Projects, Programmes & Scholarships

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