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Cell Biology / Development (histology) PhD Projects, Programs & Scholarships

We have 17 Cell Biology / Development (histology) PhD Projects, Programs & Scholarships

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  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  Epigenetic mechanisms of behavioural, placental and cognitive impairment in a neurodevelopmental model for schizophrenia
  Dr R Hager, Prof J Neill, Dr J Glazier
Applications accepted all year round

Funding Type

PhD Type

A fundamental question in disease research is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016).
  Personalized quantification and prediction of epilepsy surgery on seizure control and memory function
  Dr D Atan
Application Deadline: 25 November 2019

Funding Type

PhD Type

The University of Bristol is offering a 3.5 year full time PhD in research around Translational Health to start in 2019. This studentship is funded through GW4 BioMed MRC Doctoral Training Partnership.
  A 3D in vitro model of wound healing incorporating skin, nerves and immune cells
  Dr A M Rajnicek, Dr H M Wilson
Applications accepted all year round

Funding Type

PhD Type

Diabetes, paralysis, being bed ridden and other conditions can result in chronic wounds that fail to heal, with significant personal consequences for patients and an annual cost of £4.5-5.1 billion annually (Guest et al., 2015) to the National Health Service.
  To treat or not to treat: investigating the impact of depression and antidepressant use in pregnancy.
  Prof RM John
Application Deadline: 25 November 2019

Funding Type

PhD Type

Depression in pregnancy, often occurring in combination with anxiety and a stressful environment, increases the risk of adverse outcomes for offspring with males showing more attention deficits, cognitive problems and externalising behaviour and females tending to present with anxiety, depression and internalising symptoms.
  GW4 BioMed MRC DTP PhD studentship: Making Broken Bones Antimicrobial - Preventing Osteomyelitis Using a Targeted and Mineralising Liposomal Delivery System
  Dr WN Nishio Ayre, Prof J Birchall
Application Deadline: 25 November 2019

Funding Type

PhD Type

This project is one of a number that are in competition for funding from the ‘GW4 BioMed MRC Doctoral Training Partnership’ which is offering up to 18 studentships for entry in September/October 2019.
  Understanding interplay between genetic intra-tumour heterogeneity and the local tumour microenvironment
  Dr E Sahai
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Erik Sahai’s Group based at the Francis Crick Institute (the Crick). Intra-tumour heterogeneity represents a major challenge in the treatment of cancers.
  (MRC DTP) Developmental programming of heart disease by prenatal hypoxia: in vivo disease susceptibility and underlying epigenetic mechanisms
  Dr G Galli, Prof A Trafford
Application Deadline: 15 November 2019

Funding Type

PhD Type

A lack of oxygen to the developing fetus (prenatal hypoxia) is a common occurrence in complicated pregnancies.
  Identifying the role of glycosaminoglycans and microglia in early pathology of mucopolysaccharide diseases
  Dr B BIgger, Dr R Holley, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Mucopolysaccharidoses (MPS) are inherited metabolic disorders caused by the deficiency of specific lysosomal enzymes required for the catabolism of glycosaminoglycans (GAGs) where each MPS type lacks a specific enzyme resulting in the build-up of GAGs in all cells of the body.
  Investigating the mechanisms contributing to placental dysfunction in pregnancies complicated by diabetes: role of the hexosamine biosynthetic pathway
  Prof M Westwood, Prof J Aplin, Dr J Myers
Applications accepted all year round

Funding Type

PhD Type

Maternal diabetes is a major risk factor for fetal overgrowth, which is associated with poor outcomes including stillbirth, neonatal morbidity and increased risk of diabetes in adulthood.
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  The role of the microenvironment in regulating breast cancer metastatic colonisation
  Dr R Clarke, Dr Ciara O'Brien, Dr R Eyre
Applications accepted all year round

Funding Type

PhD Type

The metastatic spread of breast cancer cells and their colonisation of important organs is the cause of death in 95% of breast cancer.
  The role of the spliceosome protein Prpf8 in embryonic development
  Dr K Hentges
Applications accepted all year round

Funding Type

PhD Type

Errors that occur during cardiac development cause congenital heart defects (CHD). Despite the prevalence of CHD, the developmental processes that ensure the heart forms correctly are still being elucidated.
  An Organ on a Chip Platform for Biomedical Applications
  Dr P De Bank
Applications accepted all year round

Funding Type

PhD Type

Organ on a chip devices are an emerging technology which employ microfluidics to grow 3D tissues, mimicking the physiological conditions found in vivo.
  Bioactive Scaffolds for Tissue Engineering and Regenerative Medicine
  Dr P De Bank
Applications accepted all year round

Funding Type

PhD Type

Tissue engineering and regenerative medicine aim to either replace diseased or damaged tissue with a functional, laboratory-grown substitute, or stimulate the body’s own cells in order to promote repair.
  LaNts and laminins in breast cancer
  Dr K Hamill
Applications accepted all year round

Funding Type

PhD Type

The laminins are a family of proteins that make up part of specialised regions of extracellular matrix termed basement membranes.
  Molecular and cellular mechanisms of regeneration in the invertebrate chordate amphioxus
  Research Group: Biomedical Sciences Research Centre
  Dr I Somorjai
Application Deadline: 1 December 2019

Funding Type

PhD Type

Cephalochordates ("amphioxus" or "lancelet") are an ideal model for studying developmental and regenerative processes (Bertrand and Escriva 2011; Somorjai 2017).
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