Cell Biology (investigation) PhD Projects, Programmes & Scholarships

We have 31 Cell Biology (investigation) PhD Projects, Programmes & Scholarships

Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c

The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more

Supervisors: Prof G Rena, Prof E Pearson

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigation of myocardial ischemic adaptation in the presence of comorbidity factors on in vitro cell culture models

Semmelweis University Budapest Department of Pharmacology and Pharmacotherapy

Metabolic derangements, such as obesity or diabetes, are major risk factors of cardiovascular diseases. Read more

Supervisor: Dr A Görbe

Year round applications PhD Research Project Funded PhD Project (European/UK Students Only)

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Investigation of host-virus interactions

University of Leeds Faculty of Biological Sciences

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25 in the area of molecular virology. Read more

Supervisors: Dr M Stacey, Dr J N Barr

Year round applications PhD Research Project Self-Funded PhD Students Only

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In vitro modelling and investigation of skin ageing and the impact of negative stimuli

Durham University Department of Biosciences

With an ageing population and the number of over 65s predicted to be 1 in 6 by 2050 there is a real need for targeted research to enhance the quality of life of this demographic. Read more

Supervisor: Prof S Przyborski

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Interdisciplinary investigation of the role of amino acids in immunometabolic responses to metformin in human cells

University of Dundee School of Medicine

There is overwhelming evidence that inflammation contributes to the development of cardiovascular disease (CVD) but counterbalancing this is evidence from meta-analysis of randomised control trials that many existing anti-inflammatory drugs, such as COX2 inhibitors and anti-TNF drugs, tend if anything to exacerbate risk of CVD. Read more

Supervisors: Prof G Rena, Prof C Lang

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Supervisor: Dr H Sheldrake

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Investigation of the interplay between the cell cycle and Notch intracellular domain levels in presomitic mesoderm cells in somitogenesis

University of Dundee School of Life Sciences

One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more

Supervisor: Prof J K Dale

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc by Research: Investigation of coordination of cell divisions during early embryonic development

University of Dundee School of Life Sciences

Gastrulation is an essential process in early development, during which the forming ectoderm, mesoderm and endoderm take up their correct positions in the embryo. Read more

Supervisor: Prof C J Weijer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy

Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the genetic architecture of orofacial cleft: A genome-wide association study using trio data and an investigation of parent of origin and mother-children interaction effects.

University of Bristol Bristol Medical School

Rationale. Orofacial clefts (OFCs) are the most prevalent craniofacial congenital disabilities globally, occurring at a frequency of 1 out of 700 newborns. Read more

Supervisors: Dr S Lewis, Dr E Stergiakouli, Prof H Cordell

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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An investigation of the causal relationship and genetic overlap between sleep traits and physical and mental health using Mendelian randomization

University of Bristol Bristol Medical School

Rationale. Sleep has long been known to play a role in physical and mental wellbeing and sleep disruption has been observed to co-occur with a number of health conditions including. Read more

Supervisors: Dr S Lewis, Dr MR Renteria, Dr HJ Jones

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

University of Reading School of Pharmacy

Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more

Supervisor: Prof SV Vaiyapuri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

University of Leeds Faculty of Medicine and Health

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Supervisors: Prof M Wilcox, Prof A O'Neill, Dr J Freeman, Dr I Moura

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology

The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more

Supervisors: Dr C Dominguez, Prof A Fry

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Innovative Biological Scaffolds for Regenerative Replacement of Dysfunctional Heart Valves

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr H.E. Berry

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cardiac and skeletal muscle progenitor cells - driving regeneration ability by tryptophan metabolites

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Dr A.J. Smith, Dr T.S. Bowen

Year round applications PhD Research Project Self-Funded PhD Students Only

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MScR - Preserving t-tubule function in adult cardiac myocytes in short-term culture

University of Bristol School of Physiology, Pharmacology & Neuroscience

Invaginations of the sarcolemma of adult cardiac myocytes known as transverse (or t-) tubules account for up to 65% of the total sarcolemma surface and play a key role in excitation-contraction (EC) coupling and cell signalling (Hong & Shaw, 2017). Read more

Supervisors: Prof A James, Dr S Harmer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Effects of FADS2 single-nucleotide polymorphisms on clathrin-mediated endocytosis in human induced pluripotent stem cell-derived neurons

Cardiff University Cardiff School of Medicine

Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more

Supervisor: Prof A Harwood

7 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Exploring the Ubiquitin-Proteasome system’s Impact on Ageing and Disease: The Interplay of Genetics, Lifestyle, and Environment

University of Reading Department of Biomedical Sciences

Project Overview. Unravelling the molecular and cellular mechanisms driving ageing to improve human health across the lifespan is a central aim of biomedical research. Read more

Supervisor: Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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Peptide-mediated nanocarrier drug delivery for enhanced brain targeting and treatment of inflammation

The University of Manchester Faculty of Biology, Medicine and Health

This project involves the study of nanoparticles and drug delivery to the brain. The student would be required to make and characterise novel nanoparticles from special lipid molecules of various compositions more suitable for blood-brain barrier (BBB) targeting. Read more

Supervisors: Dr HS Shokr, Dr CT Tapeinos, Dr H Aojula

Year round applications PhD Research Project Self-Funded PhD Students Only

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The role of extracellular vesicles in lung epithelial cell communication in health and disease

University of Salford School of Science, Engineering and Environment

There is an opportunity to apply for a widening participation scholarship (available to UK candidates or those eligible for UK fees) can be found here. Read more

Supervisor: Dr P Miklavc

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying Mechanisms of Tyrosine Kinase Inhibitor Resistance in Breast/Cervical Cancer (with emphasis on FGFR)

Kingston University Faculty of Health, Science, Social Care and Education

FGF signalling is implicated in cancer (e.g., breast and cervical cancer) susceptibility and progression, suggesting that this powerful developmental pathway is co-opted by cancer cells. Read more

Supervisor: Dr A Chioni

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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High-performance Ultrafast Fibre Lasers for Biomedical Applications

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Dr Lin Xu, Dr Yongmin Jung . Project Description. Ultrafast lasers providing femtosecond pulses are enabling a rapidly increasing range of applications in science and industry, including physics, chemistry, medicine, biology, and materials processing. Read more

Supervisor: Dr L Xu

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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MSc By Research: Assessing health benefits of gut microbiota using host-microbe interaction models of the human gut

Aberdeen University School of Medicine, Medical Sciences & Nutrition

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Supervisors: Dr S Gratz, Prof K Scott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Supervisors: Dr G Mavria, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences

Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more

Supervisors: Dr D Ramji, Dr T Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Mendelian Randomisation for mediation analysis with multiple mediators: theory and applications

University of Bristol Bristol Medical School

Rationale. Many of an individual’s traits are observationally associated with their health outcomes. Understanding the relationships between these factors is critical to effective public health intervention. Read more

Supervisors: Dr E Sanderson, Dr R Daniel, Dr L Howe

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Born Slippy: Understanding the tribological mechanisms of fertility treatments and their impact on conception

University of Birmingham Department of Mechanical Engineering

Infertility affects 186M women in the developed world, with approximately 55M attributed to tubal patency - this is a big problem! Hysterosalpingography or HSG is a diagnostic procedure that is also an effective treatment for tubal problems. Read more

Supervisors: Dr I Stead, Dr A Hajiyavand, Prof K Dearn

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 31 Cell Biology (investigation) PhD Projects, Programmes & Scholarships

Cell Biology (investigation) PhD Projects, Programmes & Scholarships

We have 31 Cell Biology (investigation) PhD Projects, Programmes & Scholarships

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