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Cell Biology / Development (january) PhD Projects, Programs & Scholarships

We have 54 Cell Biology / Development (january) PhD Projects, Programs & Scholarships

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  UKRI Centre for Doctoral Training on Safe and Trusted Artificial Intelligence

Funding Type

PhD Type

The UKRI Centre for Doctoral Training (CDT) in Safe and Trusted Artificial Intelligence (STAI) brings together world leading experts from King's College London and Imperial College London to train a new generation of researchers in safe and trusted artificial intelligence (AI).
  UKRI Centre for Doctoral Training on Safe and Trusted Artificial Intelligence

Funding Type

PhD Type

The UKRI Centre for Doctoral Training (CDT) in Safe and Trusted Artificial Intelligence (STAI) brings together world leading experts from King's College London and Imperial College London to train a new generation of researchers in safe and trusted artificial intelligence (AI).
  Determining novel molecular regulators of necrosis controlling premature cell death
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases.
  Regulation of apoptosis-induced compensatory cell proliferation and its implications for cancer and tissue regeneration
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

In multi-cellular organisms, coordinated cell death (e.g. apoptosis) and cell replacement is critical for tissue recovery in response to stress or damage.
  Fully-funded PhD positions in several natural sciences & engineering disciplines

Funding Type

PhD Type

Join an internationally renowned scientific community with the Hector FellowPhD program. PhD students benefit not only from the experience of the program, but also from the network of Hector Fellows.
  EPSRC Centre for Doctoral Training in BioDesign Engineering

Funding Type

PhD Type

The EPSRC Centre for Doctoral Training in BioDesign Engineering aims to train the next generation of leaders at the interface of biology, engineering and data science.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round

Funding Type

PhD Type

Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  Open PhD positions - IMPRS for Heart and Lung Research

Funding Type

PhD Type

The International Max Planck Research School for Heart and Lung Research (IMPRS-HLR) offers up to ten positions to talented and enthusiastic students holding a relevant Master‘s degree.
  Analysing the factors that regulate expression of blood-brain barrier drug transporter proteins
  Dr J L Penny, Dr C Demonacos
Applications accepted all year round

Funding Type

PhD Type

In order to treat diseases associated with the central nervous system (CNS), e.g. cancer, Parkinson’s disease, depression, it is essential for therapeutic drugs to be able to penetrate into the brain.
  Basal stem cells in the lung and their recognition of dying cells
  Prof T Hussell, Dr N Fujino
Applications accepted all year round

Funding Type

PhD Type

Stem cell division and differentiation is critical for barrier repair following inflammation, but the initial trigger for this process is unknown.
  EPSRC Centre for Doctoral Training in BioDesign Engineering

Funding Type

PhD Type

The EPSRC Centre for Doctoral Training in BioDesign Engineering aims to train the next generation of leaders at the interface of biology, engineering and data science.
  Live cell imaging under extreme conditions
  Dr B Baum
Applications accepted all year round

Funding Type

PhD Type

Complex eukaryotic cells first appeared on earth over a billion years ago. It is now thought that they arose as the result of the establishment of a symbiotic partnership between an archaeal host cell and a bacterium, which went on to become the mitochondrion.
  EPSRC Centre for Doctoral Training in BioDesign Engineering

Funding Type

PhD Type

The EPSRC Centre for Doctoral Training in BioDesign Engineering aims to train the next generation of leaders at the interface of biology, engineering and data science.
  Therapeutic potential of microRNAs in medullary thyroid carcinoma
  Prof G. Hutvagner
Applications accepted all year round

Funding Type

PhD Type

The Project. Medullary thyroid cancer is a rare, aggressive neuroendocrine tumour. Treatment of MTC poses a major challenge due to its propensity of early metastasis and no available adjuvant systemic treatment options.
  Dissecting the role of MCE proteins in Cyanobacteria
  Dr V Darbari, Prof C Mullineaux
Applications accepted all year round

Funding Type

PhD Type

The School of Biological and Chemical Sciences at Queen Mary is one of the UK’s elite research centres, according to the 2014 Research Excellence Framework (REF).
  USP17 as a cancer therapeutic target
  Dr J Burrows
Applications accepted all year round

Funding Type

PhD Type

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types.
  Autoimmunity against TNF and its role in inflammatory diseases
  Dr S Jiang, Dr N Burgess-Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Tumour Necrosis Factor (TNF) is a pro-inflammatory cytokine. It regulates a complex signalling network able to trigger cell survival, as well as cell death via apoptosis or necrosis/necroptosis.
  Bispecific monoclonal antibodies for cancer immunotherapy
  Prof W Bodmer, Prof P McHugh
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Monoclonal antibodies (MCAs) are now widely used for cancer therapy. DNA recombinant technology enables the production of MCAs that target cancer specific determinants and immune cells, attracting them to the cancer cells and so killing them.
  Characterisation of DNA-protein crosslink proteolysis repair in cancer and therapy
  Prof K Ramadan, Prof B Kessler
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. DNA-protein crosslinks (DPCs) are under-investigated DNA lesions caused by the covalent attachment of proteins to DNA.
  Combining CRISPR and RNAseq to dissect molecular circuits in a hypoxic tumour microenvironment
  Prof F Buffa, Prof A Harris, Dr V D'Angiolella
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The role of the microenvironment in driving tumour progression is increasingly recognized. Hypoxia is one of the key microenvironmental changes between tumour and normal tissue, and adaptation of cancer cells to this hostile environment contributes to their malignancy and aggressive phenotype.
  Cross presentation of antigens of recombinant overlapping peptides to optimise vaccines against tumour and infectious diseases
  Dr S Jiang, Dr N Burgess-Brown
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. We have developed a technology to producing overlapping peptides - bacterial expression of an amino acid sequence corresponding to overlapping peptide sequences spanning the length of a protein of interest interspersed with enzymatic cleavage sites.
  Differentiation in colorectal cancer
  Prof W Bodmer, Prof P McHugh
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Derangement of cellular differentiation is a key step in adenocarcinoma progression. Understanding this should provide novel targets for the development of new treatments, and new approaches to diagnosis and early detection.
  Early detection of oesophageal cancer
  Prof K Vallis, Prof B Vojnovic
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Oesophageal cancer is an area of unmet clinical need; late diagnosis is one of the reasons that cure rates remain stubbornly low.
  Exosomes in oncolytic virotherapy
  Prof L Seymour, Dr K Fisher
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Oncolytic viruses promise new opportunities for targeted cancer therapy, but spread of viruses through solid tumour masses is often limited.
  Hypoxia links the unfolded proteim response with the DNA damage response
  Prof E Hammond, Prof A Giaccia
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Regions of hypoxia (insufficient oxygen) occur in most if not all solid tumours and are clinically relevant as they correlate with poor patient prognosis and therapy resistance.
  Inflammation in the tumour microenvironment
  Dr E Parkes, Dr J Rehwinkel
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. A key part of tackling cancer is understanding the tumour microenvironment, in particular the immune microenvironment.
  Investigating how cells repair DNA damage during mitosis
  Dr A Blackford, Dr D Clynes
Application Deadline: 3 March 2020

Funding Type

PhD Type

DNA damage poses a serious threat to proper chromosome segregation during cell division, and if repaired incorrectly can cause cell death or cancer.
  Investigating IGF-1 as a cancer risk factor
  Prof V Macaulay, Prof C Verrill
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The focus of this research project is the investigation of insulin-like growth factors (IGFs) as risk factors for development of cancer.
  Investigation of the contribution of redox stress to the therapy resistance of cells experiencing cycling oxygen levels
  Prof E Hammond, Dr S Conway
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. Hypoxia is a major barrier to successful cancer treatment as the more hypoxic a tumour, the less well patients respond.
  Pre-clinical investigations of POLQ inhibitors
  Dr G Higgins, Prof T Humphrey
Application Deadline: 3 March 2020

Funding Type

PhD Type

THE PROJECT. The aim of our research is to improve radiotherapy for cancer patients by making tumour cells more sensitive to radiation without affecting the sensitivity of normal cells.
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