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Cell Biology / Development (knowledge) PhD Projects, Programs & Scholarships

We have 91 Cell Biology / Development (knowledge) PhD Projects, Programs & Scholarships

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Showing 1 to 30 of 91
  Health Opportunity for Patient Empowerment in Gestational Diabetes (HOPE-GDM)
  Research Group: Chemistry and Biosciences
  Prof A M Graham, Prof R Qahwaji, Prof A Locke
Applications accepted all year round

Funding Type

PhD Type

Gestational Diabetes is a temporary condition diagnosed at 24-28 weeks gestation, where the body is unable to maintain normal blood glucose levels due to insulin resistance during pregnancy.
  Artificial Cells as Living Technology
  Prof D A Barrow, Dr O Castell
Application Deadline: 30 June 2019

Funding Type

PhD Type

The Barrow (Engineering) and Castell (Pharmacy) laboratories at Cardiff University seek motivated PhD candidates to contribute to an exciting €5M funded European collaboration in the field of synthetic biology and the development of programmable artificial cells as living technology.
  Design and Development of Artificial Nerve Grafts
  Dr K Andrews
Applications accepted all year round

Funding Type

PhD Type

Reference Number. EMRC-KDA-2018-2-PhD. Project Summary. There is a lack of viable treatment options for nerve damage and disease in humans.
  Defining the role of p53 in cancer immunotherapy
  Prof Y. Haupt, Dr S. Haupt, Dr P. Neeson
Applications accepted all year round

Funding Type

PhD Type

Despite clear evidence of an association between the tumour suppressor p53 and immunity, a gap in knowledge exists regarding its role in modulating immune responses, or its value in predicting patient responses to immunotherapy.
  Elucidating the protein interaction network of serum- and glucocorticoid-regulated kinase 1 (SGK1)
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

The phosphoinositide 3-kinase (PI3K) pathway is a master regulator of numerous cellular phenotypes associated with cancer including cell survival, proliferation, growth, altered metabolism and malignant transformation.
  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round

Funding Type

PhD Type

The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
  Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

Treatment options for the triple-negative breast cancer (TNBC) subtype of breast cancer are limited to conventional chemotherapy agents.
  Ensuring chemical safety through toxicity studies in Daphnia using state-of-the-art molecular, imaging and modelling approaches
  Prof M Viant, Dr B Campos, Dr C Rivetti, Dr I Sorrell
Application Deadline: 5 July 2019

Funding Type

PhD Type

This exciting 4-year BBSRC iCASE PhD opportunity bridges the University of Birmingham’s (*) metabolomics team and Unilever’s Safety and Environmental Assurance Centre (SEAC), both having state-of-the-art facilities and renowned research programmes, thereby creating an excellent environment for this challenging yet impactful research project.
  Eukaryotic gene expression: understanding the role of UPF1 in global mRNA processing and amyotrophic lateral sclerosis (ALS)
  Dr S Brogna
Applications accepted all year round

Funding Type

PhD Type

This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
  The endosomal network in health and disease
  Prof P J Cullen
Applications accepted all year round

Funding Type

PhD Type

Approximately 25% of the human genome encodes for integral membrane proteins (around 5,500 proteins). Efficient intracellular transport of these proteins, and associated proteins and lipids (together termed ‘cargos’), is essential for organelle biogenesis, maintenance, and quality control.
  EPSRC Centre for Doctoral Training in Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research - SABS

Funding Type

PhD Type

Good degree in the Physical or Life Sciences? Interested in biological or medical research? We offer fully-funded PhD places across the Oxford Doctoral Training Centre programmes.
  Hijacking of host cellular functions and metabolism in MRSA pathogenesis
  Dr M Letek, Dr V Behrends, Dr Y Calle
Applications accepted all year round

Funding Type

PhD Type

Applications are invited from potential PhD candidates to work at the Department of Life Sciences, University of Roehampton, supervised by Dr Michal Letek, Dr Volker Behrends, and Dr Yolanda Calle-Patino.
  PhD Project related to Spatial Proteomics of Protein quality control or Single Cell Gene Expression Dynamics
  Prof M Knop
Application Deadline: 30 July 2019

Funding Type

PhD Type

Project topic. Protein homeostasis involves control over spatio-temporal distribution of each individual protein species inside a cell.
  Understanding the role of TNFRSF11B polymorphisms in osteoprotegerin bioavailability and bone metabolism
  Dr A Daroszewska, Prof R van ‘t Hof
Applications accepted all year round

Funding Type

PhD Type

This project will focus on determining the effect of the polymorphisms of the TNFRSF11B gene, which encodes osteoprotegerin (OPG), on bone metabolism.
  Characterisation of SNA-2, a potential target for new drugs against parasitic nematodes.
  Dr B Mueller, Dr J Pettitt
Application Deadline: 28 June 2019

Funding Type

PhD Type

Spliced leader trans-splicing is a conserved and essential step involved in gene expression in many animal and human parasites that is responsible for the formation of mRNA 5’ ends in these organisms.
  Using VR to investigate the visual features that determine the effectiveness of disruptive camouflage
  Dr R Sharman, Dr G Lovell
Application Deadline: 2 August 2019

Funding Type

PhD Type

While research has begun to unpack how camouflage works, there are many gaps in our understanding. For example, in disruptive camouflage the false edges within the pattern do not attempt to exactly match the background, yet they aid concealment.
  The impact of mixed radiation and chemicals exposure on neuronal cytotoxicity, ageing and transcription
  Dr R Anderson
Application Deadline: 31 July 2019

Funding Type

PhD Type

A 3-year funded PhD studentship is available in the College of Health and Life Sciences at Brunel University London. Project description.
  KESS2 East PhD in Dentistry: Developing novel technologies to model the effects of therapies on bacterial biofilms
  Prof D W Thomas, Dr L Powell
Application Deadline: 15 July 2019

Funding Type

PhD Type

This is a fully-funded applied PhD, working between the Schools of Pharmacy and Dentistry, together with AlgiPharma AS (a Norwegian Biopharmaceutical Company.
  Investigating Noise in Ageing Cellular Power Stations
  Dr N Jones
Applications accepted all year round

Funding Type

PhD Type

PhD Project. Imperial College Mathematics. Student Background. Theoretical Physics, Mathematics/Statistics, Electrical Engineering (Biological knowledge not required).
  Understanding the cytoskeletal and biophysical changes associated with fibroblast activation during scar formation
  Dr B Stramer, Dr T Shaw
Applications accepted all year round

Funding Type

PhD Type

A PhD studentship is available to work in the laboratory of Dr. Brian Stramer (https://www.kcl.ac.uk/lsm/research/divisions/randall/research/sections/motility/stramer/index) in the Randall Centre for Cell and Molecular Biophysics, King’s College London.
  The regulation of signalling pathways in cancer initiation by Rho GTPases and the Cytoskeleton
  Dr A Elbediwy, Dr M Stolinski, Mr P Waller, Dr H Ashrafi
Applications accepted all year round

Funding Type

PhD Type

What is the reason why cells can suddenly switch to uncontrolled cellular growth? What causes the normal formation of cellular contacts and organs to stop growing when reaching their normal size to ignore normal signals and multiply uncontrollably?.
  Design and Development of Artificial Blood Vessels For Use in the Treatment of Peripheral Artery Disease
  Dr K Andrews
Applications accepted all year round

Funding Type

PhD Type

Reference Number. EMRC-KDA-2018-1-PhD. Project Summary. There is a lack of viable tissue engineering treatment options for peripheral artery disease, with many unanswered fundamental questions.
  IMPRS “From Molecules to Organisms”

Funding Type

PhD Type

Our PhD program in the life sciences places special emphasis on interdisciplinary interactions. We want to train the next generation of scientists to study complex biological processes that cannot be adequately understood within the limits of a single discipline.
  The role of isothiocyanates-derived from natural sources in uveal melanoma chemoprevention (ref: SF18/APP/McDermott)
  Prof A McDermott, Prof M Panagiotidis, Dr G Koutsidis
Applications accepted all year round

Funding Type

PhD Type

Uveal melanoma is the most frequent primary intraocular tumor, in Caucasian adults, and one that is very difficult to treat once it becomes metastatic.
  Activation of targeted DNA Damage Response as a novel therapy for Ovarian Cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer and accounts for 70% of all ovarian cancer deaths.
  Characterize the role of Treacle (TCOF1) in AKT-regulated ribosome biogenesis
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Ribosomes are essential for cell growth and proliferation, and their biogenesis requires exquisite regulation.
  Control of tissue growth and cancer by the Hippo pathway
  Dr K. Harvey, Dr C Poon
Applications accepted all year round

Funding Type

PhD Type

A new frontier in biomedical research will involve watching individual proteins work in real time, in living organs. Traditionally, researchers have drawn conclusions about gene function using indirect techniques that only allow us to infer what a gene normally does, without actually watching it work.
  Development of targeted therapy for acute myeloid leukaemia with mutations in isocitrate dehysdrogenase
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

Acute Myeloid Leukaemia (AML) is an aggressive disease with poor prognosis and development of novel treatment options is urgently needed.
  Exploration of novel approaches to anti-cancer treatment: manipulation of mutant p53
  Prof Y. Haupt, Dr S. Haupt
Applications accepted all year round

Funding Type

PhD Type

P53 is the most mutated gene in human cancer, affecting about half the cases of human cancer. We have recently identified novel regulators of mutant p53 using sophisticated loss of function whole genome high through put screen (image 1).
  Fishing for metabolic clues: Role of the Hippo/Yap pathway in reprogramming metabolism in liver cancer
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

The Hippo/Yap pathway is an evolutionarily conserved cascade that plays a fundamental role in governing organ size control, stem cell homeostasis and cancer.
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