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Cell Biology / Development (sport and exercise) PhD Projects, Programs & Scholarships

We have 9 Cell Biology / Development (sport and exercise) PhD Projects, Programs & Scholarships

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  The effects of mechanical and electrical stimulation on the maturity of tissue engineered skeletal muscle
  Prof M.P. Lewis, Dr A Capel
Applications accepted all year round

Funding Type

PhD Type

Skeletal muscle undergoes hypertrophy in response to exercise and mechanical loading, however although this response is well studied and established, the molecular sensors and signaling pathways which produce this response are not fully elucidated.
  Using a novel 3D co-culture model to define metabolic flux maps of different cancer cell types in response to physical activity
  Dr M Morris, Dr A Islam, Prof M.P. Lewis
Applications accepted all year round

Funding Type

PhD Type

During exercise, and in the presence of sufficient oxygen, glucose is metabolised by muscle cells to produce pyruvate, a metabolic intermediate which is fed into the Kreb’s cycle in the mitochondria to produce large amounts of energy.
  A multi-tissue in vitro model of osteoarthritis
  Prof M.P. Lewis, Dr D Player
Applications accepted all year round

Funding Type

PhD Type

Osteoarthritis (OA) is a joint disorder which is predominantly found in elderly individuals (Lee et al., 2013), but has recently been linked to sports participation at high levels (Vannini et al., 2016).
  Towards a Tissue Engineered Model of a Joint on a Chip
  Prof M.P. Lewis, Dr A Capel
Applications accepted all year round

Funding Type

PhD Type

This research project aims to develop a multi-tissue platform that integrates many of the structural tissue components of a musculoskeletal joint; bone, tendon, muscle, cartilage and ligament.
  Vascularisation of tissue engineered skeletal muscle
  Prof M.P. Lewis, Dr A Capel
Applications accepted all year round

Funding Type

PhD Type

Tissue engineering strategies have created a large number of functional tissues constructed from cells and matrix components over the past two decades.
  MRC DiMeN Doctoral Training Partnership: Relating skeletal muscle oxygenation dynamics to exercise intolerance mechanisms in heart failure: patient-specific interpretation of near infrared spectroscopy measurements
  Dr A.P. Benson, Dr C Ferguson, Prof S Egginton
Application Deadline: 6 January 2020

Funding Type

PhD Type

Heart failure is a complex clinical syndrome, the principal symptom of which is profound exercise intolerance (an inability to perform even day-to-day activities), the severity of which relates to disease severity.
  The effect of low-frequency and low-energy Pulsed Electromagnetic Fields (PEMFs) on muscle cell precursors: new insights into cellular mechanisms and translational research applications.
  Prof N Bury, Dr F Masieri, Dr A Rajic
Application Deadline: 1 May 2020

Funding Type

PhD Type

We are looking for a motivated graduate to join our award-nominated Biotechnology Unit Lab to work on an exciting project under the supervision of Dr Federica F.
  BBSRC Midlands Integrative Biosciences Training Partnership 2020 - Extracellular Vesicles
  Dr M Whitham
Application Deadline: 12 January 2020

Funding Type

PhD Type

Extracellular vesicles (EVs) are emerging as significant mediators of inter-tissue communication by proteins, miRNAs, lipid and metabolites in pathological contexts such as cancer, metabolic and neurological disease, but also in physiological contexts such as exercise.
  IPSCs as a model to study APP processing
  Dr S Aldred, Dr EJ Hill
Application Deadline: 12 January 2020

Funding Type

PhD Type

Amyloid precursor protein (APP) is a transmembrane protein found in many cell types around the body, most notably in brain cells such as neurons and synapses.
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