We have 29 Cell Biology (testing) PhD Projects, Programmes & Scholarships

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Cell Biology (testing) PhD Projects, Programmes & Scholarships

We have 29 Cell Biology (testing) PhD Projects, Programmes & Scholarships

Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

Testing the translational power of zebrafish for studying human heart failure. Ref: 5101

University of Exeter BBSRC South West Doctoral Training Partnership

Supervisors. Dr Matthew Winter, University of Exeter. Dr Yosuke Ono, University of Exeter. Location. Biosciences, Streatham Campus, Exeter. Read more

Supervisors: Dr M Winter, Dr YO Ono

22 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more

Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Evaluating the role of circulating proteins in cancer risk and progression using genetic and observational approaches

University of Bristol Bristol Medical School

Rationale. Circulating proteins play fundamental roles in biology and disease aetiology, including development of cancer, and are the direct targets of many drugs (1). Read more

Supervisors: Prof R Martin, Dr JY Yarmolinsky, Dr P Haycock

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Using human pluripotent stem cell-based models to study glia-associated biology in neurological diseases

Masaryk University Faculty of Medicine

Affiliation. Masaryk University, Faculty of Medicine. Study program. Ph.D. program Biomedical Sciences. Specialization. Cell and Tissue Morphology. Read more

Supervisor: Dr DB Bohačiaková

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Advancing our understanding of mycoplasma and ureaplasma infections among humans and animals

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

The Mycoplasma and Ureaplasma Group based at Cardiff Metropolitan University is seeking motivated and enthusiastic students to undertake research projects on various aspects of Mycoplasma and Ureaplasma spp infection. Read more

Supervisors: Dr M Beeton, Dr R Aicheler, Dr J Blaxland, Dr S Maddocks

Year round applications PhD Research Project Self-Funded PhD Students Only

Innovative Biological Scaffolds for Regenerative Replacement of Dysfunctional Heart Valves

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Dr H.E. Berry

Year round applications PhD Research Project Self-Funded PhD Students Only

Vascularising human mini-brains in a dish

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Blood vessels play a pivotal role in brain development and function. They promote tissue growth and survival by supplying nutrients and oxygen to surrounding tissues, signals to progenitor populations, as well as guiding neuronal migration. Read more

Supervisors: Dr PA Alexandre, Prof D Long

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Manipulation of neuroimmune responses and behaviour by infectious agents

University of Leeds Faculty of Biological Sciences

This project is available exclusively to self-funded students who wish to commence study for a PhD in the academic year 2023/24. The project focuses on how infectious agents modify the individuals that they infect and how neuroimmune responses to infection moderate behaviour changes in warm-blooded animals and humans. Read more

Supervisors: Dr G Mcconkey, Dr S Clapcote

Year round applications PhD Research Project Self-Funded PhD Students Only

NIHR Leeds BRC: An interferon diagnostic to inform early detection and prevention strategies in Ana positive CTDs

University of Leeds Faculty of Medicine and Health

Type I interferons (IFN) play a role in a wide range of rheumatic and musculoskeletal diseases (RMDs), and strong evidence suggests that measurement of IFN activity could have clinical value, although testing has not progressed into clinical settings. Read more

Supervisors: Dr F Del Galdo, Dr R Ross

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Creating patient-specific retinal organoids from human induced pluripotent stem cells for in vitro simulation of uveitis

University of Bristol Bristol Medical School

Uveitis, although uncommon, is a notable cause of visual impairment and blindness. Uveitis encompasses a range of conditions driven by both innate autoinflammatory and adaptive autoimmune CD4 T-cell responses. Read more

Supervisor: Dr P Maghsoudlou

Year round applications PhD Research Project Self-Funded PhD Students Only

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

Understanding Hormone Regulation in Skin Cancer Development and Progression

University of York York Biomedical Research Institute

Skin cancers, including melanoma and non-melanoma skin cancers, pose a significant global health burden. While the role of hormones in skin cancer development and progression remains an underexplored area, recent research has suggested potential links between hormonal regulation and skin cancer outcomes. Read more

Supervisors: Dr M Yamada, Prof T Prow

Year round applications PhD Research Project Self-Funded PhD Students Only

Ejecting infection: Understanding how epithelial tissues rid themselves of viral infections by apical extrusion

University of York York Biomedical Research Institute

Background. The epithelial tissues of our bodies use physical barriers and innate defences to fight viral infection. Read more

Supervisor: Dr S Baker

Year round applications PhD Research Project Self-Funded PhD Students Only

Improvements of asparaginase-based treatment for Childhood ALL

Cardiff University Cardiff School of Biosciences

Project Description. Most popular current treatments for childhood acute lymphoblastic leukaemia (ALL) in clinic are based on asparaginase (Raja et al 2012). Read more

Supervisors: Dr O V Gerasimenko, Dr J Gerasimenko

Year round applications PhD Research Project Self-Funded PhD Students Only

Machine learning to predict blood function – towards better haematology analysis

University of Reading Department of Biomedical Engineering

Blood represents a complex mixture of blood cells, plasma proteins, hormones, lipids, salts and water. Blood is good indicator of health, and clinically, blood samples are taken frequently to monitor health, risk of disease or success of treatments. Read more

Supervisors: Prof W Holderbaum, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

University of Leicester Molecular and Cell Biology

Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more

Supervisor: Prof S Macip

Year round applications PhD Research Project Self-Funded PhD Students Only

Investigating the connection between early embryo architecture and embryo viability

The University of Manchester Faculty of Biology, Medicine and Health

Include details on the project, outlining the objectives, methods and potential outcomes. Include details of training/techniques to be provided. Read more

Supervisors: Dr B Plusa, Dr K Dorey

Year round applications PhD Research Project Self-Funded PhD Students Only

Identifying critical pathways regulating autoimmunity in immuno-oncology and arthritis patients. Short title: IPADS (Immune PAthways for Drug Side-effects)

The University of Manchester Faculty of Biology, Medicine and Health

Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more

Supervisors: Dr S Viatte, Prof A Barton, Mr P Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

The use of life course epidemiology to support the experimental characterisation of genetic variation

University of Bristol Bristol Medical School

Project Background. There has been a rapid expansion in the generation of genetic sequence data over the last decade. Understanding the potential relevance of genetic mutations to human health remains challenging. Read more

Supervisors: Prof N Timpson, Dr L Corbin, Dr BL Lam

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

ROLE OF FOXO1 TRANSCRIPTION FACTOR IN B-CELL MALIGNANCIES

Masaryk University Faculty of Medicine

The project is focused on FoxO1 transcription factor and its role in the pathophysiology of chronic lymphocytic leukemia (CLL). Although the therapy of CLL has made several remarkable improvements, the disease still remains incurable. Read more

Supervisor: Assoc Prof Marek Mraz

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Skeletal Muscle Organoid Models for Genetic Mitochondrial Disease (ref: SF22/HLS/APP/Johnson)

Northumbria University Faculty of Health and Life Sciences

Genetic mitochondrial diseases are both clinically and genetically heterogeneous. Read more

Supervisor: Dr S Johnson

Year round applications PhD Research Project Self-Funded PhD Students Only

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

University of Leeds Faculty of Medicine and Health

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Supervisors: Prof M Wilcox, Dr K Davies, Dr A Buckley

Year round applications PhD Research Project Self-Funded PhD Students Only

Cancer: Inhibiting cell metabolism to enhance tumour cell death

University of Leeds Faculty of Medicine and Health

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Supervisors: Dr S Papa, Dr R Tooze

Year round applications PhD Research Project Self-Funded PhD Students Only

Microalgal Biorefineries

University of Sheffield Department of Chemical & Biological Engineering

A major contemporary challenge in industrial manufacturing is the development of sustainable production processes. This includes reduced resource consumption and CO2 generation, and energy efficient operations with maximised product outputs. Read more

Supervisor: Dr S Vaidyanathan

Year round applications PhD Research Project Self-Funded PhD Students Only

Algal Bioplastics

University of Sheffield Department of Chemical & Biological Engineering

Single use plastic is a major environmental concern that is urgently in need of innovative solutions. Microalgae are photosynthetic organisms that can be employed to develop processes that are environmentally sustainable. Read more

Supervisor: Dr S Vaidyanathan

Year round applications PhD Research Project Self-Funded PhD Students Only

Algae Feedstock for Food Security

University of Sheffield Department of Chemical & Biological Engineering

There is an urgent need to find innovative and sustainable solutions to meet the demands of feeding the growing global population. Read more

Supervisor: Dr S Vaidyanathan

Year round applications PhD Research Project Self-Funded PhD Students Only

Algae Feedstock for Energy Security

University of Sheffield Department of Chemical & Biological Engineering

A major challenge in contemporary energy and environmental management is to develop processes for food and energy security that are environmentally sustainable. Read more

Supervisor: Dr S Vaidyanathan

Year round applications PhD Research Project Self-Funded PhD Students Only

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