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Cell Biology (unknown) PhD Projects, Programmes & Scholarships

We have 38 Cell Biology (unknown) PhD Projects, Programmes & Scholarships

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Leveraging Functional Genomics to Understand Mitonuclear Combinations in Leber Hereditary Optic Neuropathy (Ref: FFS24/HLS/APP/WINTER)

Northumbria University Faculty of Health and Life Sciences
Mitochondria are small structures present in every cell of our body, which convert the food we eat into an energy source that cells can use. Read more
 Supervisors: Dr M Winter, Prof M Lako, Dr G Hilgen
 25 April 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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A time-resolved model for the Arabidopsis shoot apical meristem during floral transition

The James Hutton Institute Postgraduate Training
Background. Aerial parts of plants originate from pluripotent cells in the shoot apical meristem (SAM). An important determinant of crop yield but also of importance to wild species in a natural environment is the correct timing of developmental transitions. Read more
 Supervisors: Dr V Wahl, Dr R Hancock, Prof H Jonsson
 14 June 2024  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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The advancement of aqueous-Scanning Thermal Microscopy (a-SThM): Nano-scale measurement and manipulation of heat for healthcare

University of Glasgow School of Engineering
The ability to measure and manipulate heat is fundamental when studying biological processes, chemical reactions and even fundamental physics. Read more
 Supervisor: Dr P Dobson
 24 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Evaluating the impact of genotoxic aldehyde stress in premature ageing

University of Leicester Department of Chemistry
Aldehydes are highly reactive chemicals that are common pollutants and human metabolites. However, the vast majority of aldehydes’ biological functions are unknown. Read more
 Supervisors: Dr R Hopkinson, Dr K Tanaka
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular characterization of Sam68-driven cytoskeletal reorganization

University of Leicester Molecular and Cell Biology
The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more
 Supervisors: Dr C Dominguez, Prof A Fry
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Anesthesia-on-chip: Modelling the impact of fetal anesthesia on neural development

University College London UCL Great Ormond Street Institute of Child Health
A 3-year PhD Studentship on stem cell models of anaesthesia, funded by the NC3Rs, is available within the UCL GOS Institute of Child Health. Read more
 Supervisor: Dr G Galea
 30 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more
 Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Deciphering the effect of antibody-dependent cell phagocytosis and cytotoxicity (ADCC/ADCP) in the regulation of cross-presentation and antigen spreading in liver cancer.

University of Oxford Nuffield Department of Medicine
Primary liver cancers (hepatocellular carcinoma [HCC] and intrahepatic cholangiocarcinoma) are the fourth leading cause of malignancy-related mortality worldwide. Read more
 Supervisors: Dr F Galvez-Cancino, Prof I Melero Bermejo
 6 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine
Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more
 Supervisors: Dr A Saurin, Dr T Ly
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Establishing the effect of microplastic and nanoplastic exposure on inflammatory bowel disease

University of Plymouth Faculty of Health
Applications are invited for a three-year PhD studentship. The studentship will start on 01 October 2024. Project Description. Microplastics (<5 mm) are contaminating our food and mineral water. Read more
 Supervisor: Dr N Clark
 8 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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The BCAT1 CXXC Motif and Oncogenesis in Acute Myeloid Leukaemia

University of Worcester Research School
The BCAT1 gene is implicated in the pathogenesis of many cancer types, including acute myeloid leukaemia (AML)1–4. Recently, our group identified a novel antioxidant role for BCAT1 in AML cells5. Read more
 Supervisor: Dr S Coles
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Diabetes and Breast Cancer from the perspective of oestrogen receptor expression

Sheffield Hallam University Biomolecular Sciences Research Centre
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr SA Ahmed, Dr NP Peake, Dr DK Kelly
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more
 Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self funded MSc by Research or PhD in Biology: Delineating neuronal structure and function in the autism spectrum disorder neurofibromatosis type 1

University of York Department of Biology
Neurofibromatosis type 1 (NF1) is among the most common monogenetic disorders of humans and patients show a high prevalence of Autism Spectrum Disorders. Read more
 Supervisors: Dr I Hahn, Dr W Brackenbury
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Exploring the interplay between ageing, gut microbiome, and neurodegenerative diseases

University of Reading Department of Biomedical Sciences
Project Overview. Neurodegenerative disorders such as Parkinson’s and Alzheimer’s disease represent major health risks in ageing societies. Read more
 Supervisor: Dr E Kevei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences
Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more
 Supervisors: Dr HL Wright, Prof MJ Peffers
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Uncovering the mechanochemical signalling inputs that drive gastruloid axial patterning

University of Liverpool Institute of Life Course and Medical Sciences
How the early mammalian embryo converts a mass of identical cells in an organism with multiple axes of symmetry (anteroposterior, dorsoventral, mediolateral) is a critical question in developmental biology. Read more
 Supervisor: Dr D Turner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

University of Dundee School of Medicine
Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more
 Supervisors: Dr L Kang, Dr C Murdoch
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Characterisation of adrenoceptor and muscarinic receptor subtypes coupled to potassium channels in chondrocytes from bovine cartilage

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
Several outward potassium currents have been identified in bovine chondrocytes (review Mobasheri et al. 2012). These include ATP-sensitive and a Calcium-activated potassium currents (Sanches & Lopez-Zapata, 2011). Read more
 Supervisors: Dr M Hussain, Dr M Katsikogianni, Dr N Javid
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease

University of Bristol Bristol Medical School
Genome wide association studies (GWAS) have discovered many genetic associations for traits and diseases. However, most GWAS signals reside in non-coding regions (outside genes), and it is likely that GWAS variants confer their effects through modulating regulatory mechanism. Read more
 Supervisor: Dr J Min
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Charting new neuronal survival pathways in Parkinson’s disease

University of Otago Department of Biochemistry
The Neurodegenerative and Lysosomal Disease Laboratory is interested in uncovering the unknown molecular and cellular mechanisms of neurodegenerative diseases, particularly in the development of Parkinson’s disease and Batten disease. Read more
 Supervisors: Dr S Hughes, Dr IB Basik
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

University of Bradford Faculty of Life Sciences
Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
 Supervisors: Prof K Pors, Dr V Vangala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Deciphering the role(s) of Cdk1 during oocyte meiosis

University of Dundee School of Life Sciences
Meiosis is a specialised type of cell division that produces haploid daughter cells known as gametes that are important for sexual reproduction. Read more
 Supervisor: Dr F G Pelisch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: ADP-ribosylation in dementia and motor neuron disease

University of Dundee School of Life Sciences
ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more
 Supervisor: Dr L McGurk
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Genetic interactions and novel genes that regulate lignin biosynthesis and straw quality in barley

University of Dundee School of Life Sciences
Lignin is a major component of plant cell walls, and has a significant influence on the digestibility and uses of plant biomass. The lignin biosynthesis pathway has been one of the most intensively studied. Read more
 Supervisor: Prof C Halpin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health
A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
 Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Join Our Quest to Unravel the Secrets of Eukaryotic Genomes!

University of Leicester Molecular and Cell Biology
We're on the lookout for passionate PhD students who are eager to delve deep into the mysteries of our DNA. Our quest? To understand the subtle changes that determine how our genes function, both in sickness and in health. Read more
 Supervisor: Dr T Schalch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: Investigating the contextual mechanisms of WNT signalling in hypoblast vs extraembryonic mesoderm specification in early human development using stem cell models

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Prof S Hoppler, Dr C Ross
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural investigation of oncogenic splicing factors

University of Leicester Molecular and Cell Biology
More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more
 Supervisors: Dr C Dominguez, Prof I Eperon, Prof A Hudson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cell-biological mechanisms mediating primary cilium mediated interpretation of Shh signalling during vertebrate neuronal differentiation

The University of Manchester Faculty of Biology, Medicine and Health
Newborn neurons undergo extensive morphological changes as they polarise to extend axons. In the developing spinal cord, newborn neurons extend axons towards their targets in response to cues from the surrounding tissues. Read more
 Supervisors: Dr R Das, Dr S Herbert
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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