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Medical Research Council (Cambridge) Cell Biology / Development PhD Projects, Programs & Scholarships
We have 4 Medical Research Council (Cambridge) Cell Biology / Development PhD Projects, Programs & Scholarships
We have 4 Medical Research Council (Cambridge) Cell Biology / Development PhD Projects, Programs & Scholarships
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Genetic engineering of the human mitochondrial genome.
Mitochondria are intracellular organelles that are essential for life and human health. Mutations of mitochondrial DNA (mtDNA) are a major cause of inherited disease affecting ~1/8000 humans, either due to single base substitutions or deletions. Read more
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Elucidating the interplay between mitochondrial dynamics, organelle contact sites and cellular homeostasis.
Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell. Read more
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The mechanism, function, and medically-relevant dysfunction of mitochondrial complex I (NADH:ubiquinone oxidoreductase)
Complex I (NADH:ubiquinone oxidoreductase) catalyses the first step in the respiratory chain and oxidative phosphorylation. NADH oxidation and quinone reduction, coupled to proton translocation across the inner membrane. Read more
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Mitochondrial homeostasis and inflammation in Drosophila models of Parkinsons disease.
Neurodegenerative diseases such as Parkinson’s Disease are wide-spread, devastating and incurable. As over-65s are the fastest growing age-demographic, the need to better understand the molecular aetiology of these disorders is urgent. Read more
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