University of Bradford Cell Biology / Development PhD Projects, Programs & Scholarships

Research Group: Institute of Cancer Therapeutics

Dr K Pors, Dr A Mardaryev, Prof A Locke

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction.

Biofilm disruption as an initial step in a novel strategy for treatment of chronic wounds based on multi-functional liposomal nanocarriers

Research Group: Medicines Development and Pharmaceutical Sciences

Dr X Liu, Dr S Shnyder, Dr C Chang

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

The cost to the NHS of caring for patients with chronic wounds is conservatively estimated to be £4.5-5.7bn/year, or around 4% of the total expenditure on health.

Biomarkers of Genotoxic and Reprotoxic Effects after chemical exposure in vitro in human cells

Research Group: Chemistry and Biosciences

Prof D Anderson, Dr M Najafzadeh

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

In human monitoring procedures, measurements obtained from endpoints to determine genetic damage are sometimes referred to as biomarkers.

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

Research Group: Institute of Cancer Therapeutics

Dr R Falconer, Dr S Shnyder

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs).

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

Research Group: Institute of Cancer Therapeutics

Dr R Falconer, Prof P Loadman

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.

Development of transdermal protein liposomal delivery system for the treatment of dermatological diseases

Research Group: Chemistry and Biosciences

Dr M Najafzadeh, Prof D Anderson

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Biopharmaceuticals have been increasingly used in the treatment of skin diseases. However, due to the poor absorption of peptide and protein through the skin, they are usually delivered through injections.

Effect of nanoparticles on cellular conditions in lymphocytes and germ cells in vitro

Research Group: Chemistry and Biosciences

Prof D Anderson, Dr M Najafzadeh

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

The use of metals such as silver (Ag), gold (Au) and copper (Cu) as nanoparticles (NPs) and other chemicals such as Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (Najafzadeh et al., 2016) in medical and lifestyle applications has exponentially increased in recent years, yet little is still known about their impact on DNA and RNA in somatic as well as in germ cells (Habas et al 2018).

Electrophysiological changes in ion channels in human haploid and diploid (spermatozoa and lymphocytes) after nanoparticle exposure

Research Group: Chemistry and Biosciences

Dr L Shang, Dr M H Brinkworth, Prof D Anderson

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Nanomaterial-mediated delivery represents a promising technique for repro- and geno- toxicology with a potential to improve the safety and efficacy of existing methodologies, including experimental gene therapy and sperm-mediated gene transfer.

ERK5 MAPK signalling in Alzheimer’s disease

Research Group: Pharmacology and Experimental Therapeutics

Dr J Muller, Dr S Kantamneni

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available.

Formulation and evaluation of umbilical cord-derived mesenchymal stem cells exosomes and antioxidants, incorporated in nanoliposomes using microfluidics, for the treatment of solid tumours

Research Group: Chemistry and Biosciences

Dr M Najafzadeh, Prof D Anderson, Dr M Isreb

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

This project uses the Cord blood Stem Cells from healthy control and the white blood cells of blood cancer patients to investigate the efficacy and genotoxicity of different compounds in them by using various genetic endpoints.