University of East Anglia Featured PhD Programmes
Sheffield Hallam University Featured PhD Programmes
Lancaster University Featured PhD Programmes
10 miles

University of Leeds Cell Biology / Development PhD Projects, Programs & Scholarships

We have 28 University of Leeds Cell Biology / Development PhD Projects, Programs & Scholarships

  • Cell Biology / Development×
  • University of Leeds×
  • clear all
Order by 
Showing 1 to 15 of 28
  A ‘Metastasis-On-A-Chip’ Microphysiological Model of Cancer Metastasis to Bone
  Dr M Amer, Dr V Pensabene, Prof F Meldrum
Application Deadline: 1 July 2020

Funding Type

PhD Type

Bone is a frequent site of cancer metastases and usually indicates poor clinical prognosis. Metastasis of tumour cells in the bone marrow is a dynamic process, and cell behaviour is regulated by three-dimensional (3D) cell-cell and cell-matrix interactions with its microenvironment.
  A mechanistic understanding of allosteric regulation of neuronal sodium-activated potassium channels
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr S Muench, Dr A Kalli
Applications accepted all year round

Funding Type

PhD Type

The sodium-activated potassium channel KNa1.1 (KCNT1, Slack, Slo2.2) is found in neurons and couples sodium influx to excitability.
  Ca2+ signalling in neurodegeneration and Alzheimer’s disease
  Research Group: School of Biology
  Prof I A Hope
Applications accepted all year round

Funding Type

PhD Type

Human variants of the ryanodine receptor, the main intracellular calcium ion channel, could be responsible for Alzheimer’s disease.
  Control and inhibition of virus replication
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A.K Tuplin
Applications accepted all year round

Funding Type

PhD Type


The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specificaly Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.
  Epigenetics and Cancer: Development of Novel Tools to Determine how Aberrant V(D)J Recombination Reactions Cause Leukaemia
  Research Group: School of Molecular and Cellular Biology
  Dr J Boyes
Applications accepted all year round

Funding Type

PhD Type

V(D)J recombination generates a highly diverse set of immunoglobulin and T cell receptor genes to enable vertebrates to fight a vast range of infections.
  How protective signals from the gut modify neuronal activity and behaviour, using C. elegans as a model system.
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr P van Oosten-Hawle, Prof N Cohen
Applications accepted all year round

Funding Type

PhD Type

Amyloid protein misfolding leading to loss of neuronal function are fundamental pathogenic mechanisms of numerous age-associated neurodegenerative diseases, including Alzheimer’s (AD).
  Identifying cardiac disease markers using non-lethal ’biopsy’ of cells.
  Research Group: School of Biomedical Sciences
  Dr A.J. Smith
Applications accepted all year round

Funding Type

PhD Type

This project will build on our recent exciting discovery that a novel chemical tool, the polymer styrene maleic acid (SMA), can ‘biopsy’ human vascular cells, extracting proteins from the membrane without killing the cells.
  Learning from plant cell walls as a path for innovations in food and material sciences
  Dr Y Benitez-Alfonso, Dr C Bosch
Applications accepted all year round

Funding Type

PhD Type

The research will dissect the structural factors controlling cell walls and cell communication for two main purposes. to improve the health value of food crops and to design strategies for the valorisation of wasted plant materials.
  Molecular, biochemical and developmental analysis of root traits for low P adaptation in foxtail millet.
  Prof A Baker, Dr S Kepinski
Applications accepted all year round

Funding Type

PhD Type

Phosphorus is an essential macronutrient for plant growth and cannot be replaced by any other element. It is the second most limiting nutrient after N.
  Nanoinjection: a single molecule technique to study amyloid toxicity in neurons
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford, Dr P Actis
Applications accepted all year round

Funding Type

PhD Type

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.
  Structural insights into ligand binding and channel gating in ATP-gated P2X7 receptor
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr S Muench
Applications accepted all year round

Funding Type

PhD Type

P2X7 receptor, belonging to the ATP-gated ion channel P2X receptor family, exhibits distinct functional and pharmacological properties that are crucial for its role in innate immunity and inflammatory diseases and cancers (Jiang et al., 2013; Caseley et al., 2014; Roger et al., 2014; Wei et al., 2018).
  TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr I Wood
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
  Enhancing Oncolytic Virus-induced Immunotherapy using Eicosapentaenoic Acid (EPA)
  Dr F Errington-Mais, Dr MA Volpato
Applications accepted all year round

Funding Type

PhD Type

Breast cancer is the most commonly diagnosed cancer in women with triple-negative breast cancer (TNBC) having the worst prognosis, highest death rate and lowest overall survival.
  Epigenetic therapy using ultrasound-mediated microbubble drug delivery for cancer treatment
  Dr E Valleley, Dr L Coletta
Applications accepted all year round

Funding Type

PhD Type

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (such as DNA methyltransferase inhibitors), as a potential combination therapy for colorectal cancer (CRC).
Show 10 15 30 per page


FindAPhD. Copyright 2005-2020
All rights reserved.