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University of Liverpool Cell Biology / Development PhD Projects, Programs & Scholarships

We have 66 University of Liverpool Cell Biology / Development PhD Projects, Programs & Scholarships

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  ’Mechano-culture’ of stem cells for tissue engineering and regenerative medicine
  Dr JR Henstock
Applications accepted all year round
OVERVIEW. The core objective of the PhD is to develop a new pneumatic (hydrostatic) pressure bioreactor for manufacturing mesenchymal stem cells.
  Characterisation of cell death mechanisms in cancer: protein interactions in p53/PERP-mediated apoptosis
  Prof L Paraoan, Dr I Prior
Applications accepted all year round
Apoptosis or programmed cell death is a tightly regulated intrinsic process of programmed cell death used by cells in all multicellular organisms, including humans, to control tissue homeostasis or to initiate their own death following malfunction or damage beyond repair.
  Characterization and functional analysis of a novel cancer-associated gene
  Dr JP de Magalhaes
Applications accepted all year round
In order to identify new candidate cancer-related genes, our lab developed a bioinformatics “guilt-by-association” method to identify and rank genes that are co-expressed with known cancer-related genes.
  Connective Tissue Fibrosis: Understanding basic biological mechanisms and the development of targeted therapies
  Prof G Bou-Gharios
Applications accepted all year round
The PhD proposal is aimed at understanding some of the fundamental mechanism(s) that control extracellular matrix (ECM) proteins and to develop new technologies and therapeutic based on changes in fibroblast gene expression profiling and surface antibodies during the development of connective tissue fibrosis.
  Developing co-culture systems to enable the modelling of interactions between cells of the synovial joint
  Dr S Tew
Applications accepted all year round
Synovial joints such as the knees and hips can be considered as multi tissue organs and crosstalk between the tissue types contributes strongly to the maintenance of their effective mechanical function.
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round
We aim to understand how MMP13 is transcriptionally regulated and whether a newly identified enhancer is involved in normal and osteoarthritic cartilage.
  Diabetic osteoarthritis : Investigating its causes and discovering interventions using tissue engineered human cartilage
  Dr JR Henstock
Applications accepted all year round
OVERVIEW. People with diabetes have more than twice the risk of developing osteoarthritis than the general population.
  Endocytosis in joint health and disease
  Dr K Yamamoto, Prof G Bou-Gharios
Applications accepted all year round
Osteoarthritis (OA) is the most prevalent age-related joint disorder that causes pain and disability. Over 8 million people suffer from OA in the UK alone, but there are no disease-modifying drugs available.
  Environmental regulation of mRNA decay in adult stem cells
  Dr S Tew
Applications accepted all year round
How cells control the rate at which specific mRNAs are destroyed critically influences gene expression levels and cell function.
  Identifying nutrient and pesticide modulation of ion channels with Artificial Intelligence (AI)
  Dr R Barrett-Jolley
Application Deadline: 11 January 2019
Many pesticides and food nutrients that animals (including people) are exposed to can have subtle, but potentially dangerous toxic effects by interactions with ion channels.
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