University of Liverpool Cell Biology PhD Projects, Programmes & Scholarships

We have 31 University of Liverpool Cell Biology PhD Projects, Programmes & Scholarships

Repeat Physical Traumas an initiator for motor neuron disease (MND): an insight from professional rugby

University of Liverpool Institute of Life Course and Medical Sciences

Motor Neuron Disease (MND) is a devastating condition affecting neuronal cells responsible for voluntary muscle movement. The risk of developing MND is 1 in 300, predominantly in individuals over 50. Read more

Supervisors: Dr C Staunton, Prof A McArdle

20 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

More Details

Probing Death Decisions from Morphogen Gradient Fields

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Morphogen gradient scaling is one of the hottest fields in developmental biology at the moment. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt, so that organs of different sizes show morphological structures which are proportioned. Read more

Supervisor: Dr MM Merino

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Using single cell transcriptomic and blood proteomic data to understand how pancreatic cancer causes diabetes and to find ways to detect the cancer earlier

University of Liverpool Department of Molecular and Clinical Cancer Medicine

Pancreatic cancer is the deadliest of the common cancers. Five-year survival remains low at 12%. Sadly for 80% of patients, by the time their cancer is diagnosed it has spread to distant organs making them ineligible for potentially curative surgery. Read more

Supervisor: Prof E Costello

23 May 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Last chance to apply

Development of novel therapies for Hirschsprung’s Disease

University of Liverpool Faculty of Health and Life Science

As a PhD student, you'll be part of a groundbreaking project aiming to revolutionise the treatment landscape for Hirschsprung's Disease (HSCR). Read more

Supervisors: Miss RH Harwood, Dr B Wilm, Miss SA Almond

26 April 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

More Details

Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics

Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more

Supervisor: Dr RB Burton

1 July 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more

Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Creation of cell lines modelling complex karyotype in B cell lymphomas using CRISPR/Cas9

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Chronic lymphocytic leukaemia (CLL) and diffuse large B cell lymphoma (DLBCL) make up more than half of all the newly diagnosed cases of non-Hodgkin’s lymphoma (NHL), the 6th most common cancer in the UK. Read more

Supervisors: Dr J Slupsky, Dr N Kalakonda, Dr M Glenn

1 May 2024 PhD Research Project Self-Funded PhD Students Only

More Details

Identifying age-related extracellular microenvironment in dental tissues

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Periodontal disease is the sixth most globally prevalent age-related disease and a leading cause of tooth loss, significantly impacting quality of life and healthy ageing. Read more

Supervisors: Dr K Yamamoto, Prof FJ Jarad

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Elucidation of a new pathological mechanism for brittle bone disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Alterations in reparative dentinogenesis with ageing, gender and genetic predisposition

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Dental pulp exposure caused by tooth decay or injury can lead to life-threatening infections. Following injury, reparative dentinogenesis serves a vital purpose through the accelerated generation of tertiary dentine, comprising mineral and type I collagen. Read more

Supervisors: Dr EG Laird, Dr N Longridge, Prof FJ Jarad

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences

Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more

Supervisor: Prof LG Yu

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences

Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more

Supervisors: Dr HL Wright, Prof MJ Peffers

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

University of Liverpool Institute of Life Course and Medical Sciences

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Supervisor: Dr VPV Pekovic-Vaughan

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences

Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more

Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Investigating the role of Aquaporins in age related diseases

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more

Supervisor: Dr C Staunton

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Control of bone shape and function by the extracellular matrix Fibrillin-1

University of Liverpool Institute of Life Course and Medical Sciences

Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Uncovering the mechanochemical signalling inputs that drive gastruloid axial patterning

University of Liverpool Institute of Life Course and Medical Sciences

How the early mammalian embryo converts a mass of identical cells in an organism with multiple axes of symmetry (anteroposterior, dorsoventral, mediolateral) is a critical question in developmental biology. Read more

Supervisor: Dr D Turner

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Investigating the role of oxidative metabolites in joint destruction in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress in alkaptonuria (AKU) and associated conditions. Read more

Supervisors: Dr BN Norman, Dr JH Hughes, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Exploring tyrosine metabolism as a source of oxidative stress

University of Liverpool Institute of Life Course and Medical Sciences

We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress associated with tyrosine metabolism. Read more

Supervisors: Dr BN Norman, Dr JH Hughes, Prof L Ranganath

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

More Details

The effect of low protein diet on the development of the neuromuscular system

University of Liverpool Institute of Life Course and Medical Sciences

Age-related sarcopenia is characterised by reduction in the number of myofibres and motor neurons and an additional weakening of the remaining fibres, causing reduction in muscle mass and function. Read more

Supervisor: Dr A Vasilaki

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Urokinase-plasminogen activator as a target to block osteoarthritic cartilage destruction

University of Liverpool Institute of Life Course and Medical Sciences

Osteoarthritis (OA) is one of the major causes of disability globally, which is particularly significant in an ageing population. Read more

Supervisor: Dr D Wilkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Determination of the non-coding RNAs in the knee joint tissues of dogs at differing risk to cranial cruciate ligament rupture.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Background. The cranial cruciate ligment (CCL) is the most frequently damaged ligament of the canine knee joint following injuries and age-related ligament breakdown, leading to the development of osteoarthritis (OA). Read more

Supervisors: Prof E Comerford, Prof M Peffers

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Biological pathways supporting the formation and function of chromatin (Scholarship)

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Every cell in our body contains the same DNA yet each cell expresses a different set of genes. These changes in gene expression are heavily influenced by histone proteins, their role in packaging DNA into chromatin and the “epigenetic” information they carry. Read more

Supervisor: Dr CM Hammond

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Exploring the roles of dynamic atypical protein phosphorylation in cancer

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Proteins are extensively regulated by dynamic, often reversible post-translational modifications (PTMs). This process allows cells to respond rapidly to environmental factors, be that e.g. Read more

Supervisors: Prof C E Eyers, Prof A Jones

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

A 3D-Printed Blood-Brain-Barrier-on-a-Chip for Agrochemical Permeability Studies – CASE Studentship

University of Liverpool Department of Physics

The blood-brain barrier (BBB) tightly regulates the flow of material between the bloodstream and the brain. One of the big problems faced by a range of sectors, from pharmaceuticals to agrochemicals, is understanding how compounds interact with and cross this barrier. Read more

Supervisors: Dr J Forth, Dr D Dickens

1 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

More Details

Investigating the cellular functions of Trappc9 in brain development and microcephaly

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more

Supervisors: Dr A Plagge, Dr T Zech

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

Hepatic Models to personalise cancer chemotherapy

University of Liverpool Department of Pharmacology and Therapeutics

The most commonly used chemotherapy regimens for colorectal cancer with liver metastases are oxaliplatin combined with 5-FU and leucovorin, i.e. Read more

Supervisors: Prof C Goldring, Dr A Chadwick, Prof IC Copple, Dr S Pushpakom

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

We have 31 University of Liverpool Cell Biology PhD Projects, Programmes & Scholarships

University of Liverpool Cell Biology PhD Projects, Programmes & Scholarships

We have 31 University of Liverpool Cell Biology PhD Projects, Programmes & Scholarships

University of Liverpool

Select your nearest city

Do you want hassle-free information and advice?