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We have 17 University of Sheffield Cell Biology PhD Projects, Programmes & Scholarships

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University of Sheffield Cell Biology PhD Projects, Programmes & Scholarships

We have 17 University of Sheffield Cell Biology PhD Projects, Programmes & Scholarships

University of Sheffield

Our University has a reputation for world-class teaching and research excellence across a variety of disciplines

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How does glycolysis influence the oral environment during caries and periodontitis?

University of Sheffield School of Clinical Dentistry
Glycolysis plays a pivotal role during energy metabolism and cellular responses in oral health and pathology. It is a crucial metabolic pathway for energy production, especially in inflammation or infection scenario, that is essential for maintaining tissue integrity and function in the gingiva and dental pulp. Read more
 Supervisors: Dr C M Neves, Prof G Stafford
 31 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Targeting dormant cancer cells in myeloma

University of Sheffield School of Medicine and Population Health
Multiple myeloma is the second most common blood cancer and remains essentially incurable. Chemotherapy is effective at reducing tumour and extends survival, but it never fully eradicates disease, so patients face inevitable relapse. Read more
 Supervisors: Dr A Green, Prof S El-Khamisy
 31 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Therapy for NBAS-related disorder

University of Sheffield School of Medicine and Population Health
It is very well recognised that rare diseases offer the potential to uncover new information about mechanisms underlying a range of phenotypes. Read more
 Supervisor: Dr M Balasubramanian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Role of primary cilia in skeletal muscle stem cells and muscle regeneration

University of Sheffield School of Biosciences
Primary cilia are cellular organelles present at the surface of many cell types in vertebrates. In recent years, they have been shown to play essential roles in relaying signalling information from the environment to the cell. Read more
 Supervisor: Dr A G Borycki
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Control of skeletal muscle regeneration and aging by cell signalling

University of Sheffield School of Biosciences
The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells. Read more
 Supervisor: Dr A G Borycki
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Uncharted Territories: Investigating the Impact of Follicular Fluid Extracellular Vesicles on Spermatozoa Function

University of Sheffield School of Medicine and Population Health
The intricate dynamics underlying successful mammalian reproduction continue to captivate scientific inquiry. However, the mechanisms governing the interaction between spermatozoa and the female reproductive tract remain elusive. Read more
 Supervisor: Prof A Fazeli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Effect of androgens on preantral follicle development

University of Sheffield School of Medicine and Population Health
Polycystic ovary syndrome (PCOS) is a condition that affects >5% of women of reproductive age and is the most common cause of menstrual dysfunction and is associated with metabolic abnormalities and increased risk to long-term health. Read more
 Supervisors: Dr M Fenwick, Dr N Krone
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterisation of scavenger receptor ligand binding.

University of Sheffield School of Biosciences
Scavenger receptors have been identified as being important in Human disease and normal physiological responses. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously. Read more
 Supervisors: Dr S Brown, Dr I Evans
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The regulation of scavenger receptors in cancer

University of Sheffield School of Biosciences
The expression of some scavenger receptors has been identified as being poor for cancer prognosis. Scavenger receptors are a large family of cell surface receptors that are expressed ubiquitously in the Human body. Read more
 Supervisors: Dr S Brown, Dr C Guo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer cells ‘feed’ on extracellular matrix components under starvation conditions: how can they do it?

University of Sheffield School of Biosciences
Background. The tumour microenvironment (TME) has a key role in promoting tumour formation and progression. In breast and pancreatic cancers, this accompanied by the accumulation of extracellular matrix (ECM) in the TME. Read more
 Supervisors: Dr E Rainero, Dr A Peden
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identification of the molecular pathways that guide tissue regeneration

University of Sheffield School of Biosciences
The study of regenerative biology aims to elucidate the innate ability of organisms to replace tissues or organs after they have been removed or damaged. Read more
 Supervisor: Dr H Roehl
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

University of Sheffield School of Biosciences
Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more
 Supervisor: Dr C Guo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microalgal Biorefineries

University of Sheffield Department of Chemical & Biological Engineering
A major contemporary challenge in industrial manufacturing is the development of sustainable production processes. This includes reduced resource consumption and CO2 generation, and energy efficient operations with maximised product outputs. Read more
 Supervisor: Dr S Vaidyanathan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Algal Bioplastics

University of Sheffield Department of Chemical & Biological Engineering
Single use plastic is a major environmental concern that is urgently in need of innovative solutions. Microalgae are photosynthetic organisms that can be employed to develop processes that are environmentally sustainable. Read more
 Supervisor: Dr S Vaidyanathan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Algae Feedstock for Food Security

University of Sheffield Department of Chemical & Biological Engineering
There is an urgent need to find innovative and sustainable solutions to meet the demands of feeding the growing global population. Read more
 Supervisor: Dr S Vaidyanathan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Algae Feedstock for Energy Security

University of Sheffield Department of Chemical & Biological Engineering
A major challenge in contemporary energy and environmental management is to develop processes for food and energy security that are environmentally sustainable. Read more
 Supervisor: Dr S Vaidyanathan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the Mechanobiology of Cancer

University of Sheffield School of Biosciences
Cancer is the second-leading cause for death globally and there is a high demand for novel approaches to understand and treat cancer. Read more
 Supervisor: Dr K Erdmann
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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