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Cell Biology PhD Projects, Programmes & Scholarships

We have 501 Cell Biology PhD Projects, Programmes & Scholarships

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We have 501 Cell Biology PhD Projects, Programmes & Scholarships

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A biologic drug blocking ROR2 for disease modification in osteoarthritis

We reported that silencing the WNT receptor ROR2 results in protection from cartilage breakdown and rapid pain relief in a murine model of osteoarthritis and in chondrogenesis in vitro and in vivo with human osteoarthritic chondrocytes (Thorup et al. Read more

Mathematical modelling of herpes simplex virus transmission in 2- and 3- dimensions

This is an exciting opportunity to undertake an EPSRC-funded PhD that will combine experimental work with mathematical modelling to describe the transmission of the human pathogen herpes simplex virus (HSV) in human cells and tissue models, and develop a comprehensive tool for assessing the parameters that influence virus transmission. Read more

Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins

Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more

Determining novel molecular regulators of necrosis controlling premature cell death

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more

Coordination between RNAPII transcription and DNA replication

RNA Pol II (RNAPII) transcription and DNA replication are the two essential-for-life processes that use as a substrate the DNA in our cells, allowing the¬¬m to express the content of their genetic information and to propagate these instructions to daughter cells. Read more

Cell-type dependent pharmacological regulation of cellular mitophagy for therapeutic application in Parkinson’s disease

The cellular quality-control process of mitophagy, entailing selective degradation of defective mitochondria (following damage to their DNA) by the process of autophagy, has attracted considerable research interest. Read more

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