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Cell Biology (genomic) PhD Projects, Programmes & Scholarships

We have 38 Cell Biology (genomic) PhD Projects, Programmes & Scholarships

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We have 38 Cell Biology (genomic) PhD Projects, Programmes & Scholarships

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Single-cell analysis of stress memory in plants

Plants are sessile organisms that are known for their adaptive plasticity to the changing environment. Environmental changes cannot only influence gene expression patterns but also affect the stability of the genome. Read more

Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease

Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more

De Novo Mutations and Human Disease

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more

De Novo Mutations and Human Disease

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more

Building the skull - normal and abnormal development

Using a combination of patient samples and mouse models, we study the causes and developmental origins of skull malformation. The work ranges from screening human DNA for new mutations, to use of genome editing and single cell transcriptomics to model the developmental causes of these malformations in mice. Read more

Transcriptional control of vascular development

Sprouting of new capillaries from pre-existing vessels (angiogenesis) promotes the formation of almost all blood vessels during development, growth and tissue regeneration. Read more

Does membrane repair fail to alert the immune system to disease?

The cGAMP-synthase cGAS recognises microbial or self-DNA to activate STING and induce the release of pro-inflammatory molecules. But cytoplasmic DNA is also particularly abundant in cancer cells, under the form of genomic structures called ‘micronuclei’. Read more

Evolution of vertebrate blood vessels

The blood vessels are the core elements of the circulatory system of animals, and their malfunction is related to most human diseases including cancer and heart attacks. Read more

How do viral capsids subvert host defences and deliver viral genomes into the host cell nucleus?

Seeking a curious PhD student to join our interdisciplinary Structural Virology and Molecular. Machines group at the EMBL Australia Node in Single Molecule Science (SMS) at UNSW Sydney. Read more

Novel non-coding RNAs in regulating cancer epigenome

This opportunity will remain open until a suitable candidate has been found and so early applications are encouraged. Cancer-associated changes in gene expression and genome stability are often attributed to variations in DNA methylation. Read more

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