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Cell Biology (metabolism) PhD Projects, Programmes & Scholarships
We have 52 Cell Biology (metabolism) PhD Projects, Programmes & Scholarships
We have 52 Cell Biology (metabolism) PhD Projects, Programmes & Scholarships
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Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism
24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g. Read more
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Investigating the coupling between the circadian clock, metabolism and the environment in cyanobacteria
This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more
A role for cholesterol metabolism in neurodevelopmental disorder
Microdeletions and duplications of the chromosome 15q11.2 region have been identified as a high penetrant risk copy number variance (CNV) to autism and schizophrenia. CYFIP1 (Cytoplasmic FMR1-interacting protein 1) is generally believed to be the causal risk gene in this CNV. Read more
Defective Branched chain amino acid (BCAA) metabolism links adipose tissue dysfunction and type 2 diabetes
Branched chain amino acids (BCAA; including leucine, isoleucine and valine) are essential amino acid that are metabolized in adipose tissues. Read more
Understanding how glucagon-like peptide-1 (GLP1) and gastric inhibitory polypeptide (GIP) receptors contribute to metabolism in complex tissues.
Our labs are focused on developing and using novel technologies to address challenging problems in cellular metabolism, with translational relevance for patients. Read more
The role of mitochondrial fission process 1 (Mtfp1) in pancreatic β- cells
Failure of β-cells to secrete enough insulin contributes to the development of type 2 diabetes, which affects 462 million people worldwide. Read more
Investigate the novel therapeutic potential for treating heart failure in diabetes.
Heart failure is the most common cause of mortality in diabetes patients, but current diabetes therapies have a limited impact on the incidence of heart failure in diabetic populations. Read more
Investigating the role of autophagy and mitochondrial function in leukaemic stem cells
Our lab is interested in biological processes that contribute to drug resistance in myeloid leukaemias, with particular focus on leukaemic stem cells (LSCs). Read more
Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
The impact of gut microbiome and diet interplay on neurodegeneration
Neurodegenerative disorders such as Parkinson’s, Alzheimer’s or Huntington’s disease represent major health risks of ageing societies. Read more
12 fully funded Ph.D. positions at the Cologne Graduate School of Ageing Research
The Cologne Graduate School of Ageing Research (CGA) in Germany is a joint venture of the University of Excellence Cluster on Stress Responses in Aging-Associated Diseases (CECAD), the University and University Hospital Cologne, the Max Planck Institute for Biology of Ageing and the Max Planck Institute for Metabolism Research. Read more
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Exploiting metabolic vulnerabilities induced by dietary restriction as novel therapies for infant leukaemia
TO APPLY, CLICK 'INSTITUTION WEBSITE'. Infant leukaemia is an aggressive malignancy with cure rates of less than 50%. Importantly, despite large international trials, there has been no improvement in survival over the last 2 decades. Read more
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Dissecting the role of Activin signalling in Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is currently the fourth leading cause of cancer associated mortality with <7% patients surviving for 5 years following diagnosis. Read more
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Covalent Recruitment of Polymer Therapeutics
This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more