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Cell Biology (metabolism) PhD Projects, Programmes & Scholarships
We have 46 Cell Biology (metabolism) PhD Projects, Programmes & Scholarships
We have 46 Cell Biology (metabolism) PhD Projects, Programmes & Scholarships
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Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism
24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g. Read more
A role for cholesterol metabolism in neurodevelopmental disorder
Microdeletions and duplications of the chromosome 15q11.2 region have been identified as a high penetrant risk copy number variance (CNV) to autism and schizophrenia. CYFIP1 (Cytoplasmic FMR1-interacting protein 1) is generally believed to be the causal risk gene in this CNV. Read more
Defective Branched chain amino acid (BCAA) metabolism links adipose tissue dysfunction and type 2 diabetes
Branched chain amino acids (BCAA; including leucine, isoleucine and valine) are essential amino acid that are metabolized in adipose tissues. Read more
Last chance to apply
Understanding how glucagon-like peptide-1 (GLP1) and gastric inhibitory polypeptide (GIP) receptors contribute to metabolism in complex tissues.
Our labs are focused on developing and using novel technologies to address challenging problems in cellular metabolism, with translational relevance for patients. Read more
PhD Opportunity in Pathology: Developing a Combined Oncometabolite and Tumour Microenvironment Map of Renal Cell Cancer
A fully funded PhD studentship is available under the supervision of Professor David Harrison and Dr Alison Dickson in the area of multi-modal imaging of cancer tissue. Read more
PhD Studentship - Investigating the role of CXCR2 signalling in neutrophils in hepatic steatosis
Overview. Liver disease is currently the third biggest cause of premature deaths in the UK and fatty liver disease is predicted to be the leading cause of liver disease in the next decade. . Read more
Investigate the novel therapeutic potential for treating heart failure in diabetes.
Heart failure is the most common cause of mortality in diabetes patients, but current diabetes therapies have a limited impact on the incidence of heart failure in diabetic populations. Read more
Investigating the role of autophagy and mitochondrial function in leukaemic stem cells
Our lab is interested in biological processes that contribute to drug resistance in myeloid leukaemias, with particular focus on leukaemic stem cells (LSCs). Read more
Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
The impact of gut microbiome and diet interplay on neurodegeneration
Neurodegenerative disorders such as Parkinson’s, Alzheimer’s or Huntington’s disease represent major health risks of ageing societies. Read more
12 fully funded Ph.D. positions at the Cologne Graduate School of Ageing Research
The Cologne Graduate School of Ageing Research (CGA) in Germany is a joint venture of the University of Excellence Cluster on Stress Responses in Aging-Associated Diseases (CECAD), the University and University Hospital Cologne, the Max Planck Institute for Biology of Ageing and the Max Planck Institute for Metabolism Research. Read more
Last chance to apply
Fully Funded Dunhill Medical Trust Healthy lifespan Institute DTP Studentship: The role of adrenomedullin and its receptors in age-related in organ dysfunction.
This 3.5 year studentship is part of research within the Healthy Lifespan Institute (HELSI) at The University of Sheffield. HELSI is dedicated to the understanding and prevention of multimorbidity (the presence of two or more chronic health conditions that create disability and reduce quality of life). Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Last chance to apply
Deciphering the role of white and brown adipocytes in metabolic disease
Our work focuses on understanding how obesity drives the development of type 2 diabetes and cardiovascular disease. Specifically, it aims to decipher molecular determinants of adipocyte number and distribution within the body; key factors of susceptibility to obesity-associated cardiometabolic diseases. Read more
Evaluation of MCT1s role in chromatin remodelling and metabolomics changes involved in cancer progression
Monocarboxylate transporter 1 (MCT1) is a transmembrane protein involved in cell metabolism and mediates transport of monocarboxylates (such as pyruvate {a metabolic substrate} and lactate {a metabolic by product}) in and out of the cell. Read more