We have 5 Chemistry (clinical pharmacology) PhD Projects, Programmes & Scholarships

Cancer and the long-term toxicities sustained from treatment remain a public health issue for adult and paediatric patients. The spread of tumour cells is believed to account for up to 90% of cancer-related morbidities. Read more

Supervisor: Dr O Piskareva

1 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Study on the role of pharmacokinetic mechanisms in the anticancer drug resistance and possibility of their modulation

Charles University Faculty of Pharmacy

Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology . Drug resistance represents a critical obstacle to successful anticancer pharmacotherapy. Read more

Supervisor: Assoc Prof J Hofman

30 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 5 Chemistry (clinical pharmacology) PhD Projects, Programmes & Scholarships

Chemistry (clinical pharmacology) PhD Projects, Programmes & Scholarships

We have 5 Chemistry (clinical pharmacology) PhD Projects, Programmes & Scholarships

From bench to pre-clinical evaluation: a novel nucleic acid vaccine targeting tumour-associated antigens

Study on the role of pharmacokinetic mechanisms in the anticancer drug resistance and possibility of their modulation

New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

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