Toxicology (breast) PhD Projects, Programmes & Scholarships

We have 5 Toxicology (breast) PhD Projects, Programmes & Scholarships

Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences

Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more

Supervisor: Prof LG Yu

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics

Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more

Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru

Year round applications PhD Research Project Self-Funded PhD Students Only

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Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

University of Liverpool Department of Pharmacology and Therapeutics

Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more

Supervisors: Dr M Cross, Prof C Goldring

Year round applications PhD Research Project Self-Funded PhD Students Only

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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

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We have 5 Toxicology (breast) PhD Projects, Programmes & Scholarships

Toxicology (breast) PhD Projects, Programmes & Scholarships

We have 5 Toxicology (breast) PhD Projects, Programmes & Scholarships

Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

Analysing the role of statins in cardiovascular protection

Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

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