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We have 19 Toxicology (pharmacology) PhD Projects, Programmes & Scholarships

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Toxicology (pharmacology) PhD Projects, Programmes & Scholarships

We have 19 Toxicology (pharmacology) PhD Projects, Programmes & Scholarships

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Pharmacological and toxicological effects of pollutants on the cardiovascular system

Charles University Faculty of Pharmacy
Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology. The majority of the world's population lives in medium or large cities where human activities (industry, transport, etc.) have a direct impact on the production of pollutants. Read more
 Supervisor: Prof P Mladěnka
 29 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Hepatic Models to personalise cancer chemotherapy

University of Liverpool Department of Pharmacology and Therapeutics
The most commonly used chemotherapy regimens for colorectal cancer with liver metastases are oxaliplatin combined with 5-FU and leucovorin, i.e. Read more
 Supervisors: Prof C Goldring, Dr A Chadwick, Prof IC Copple, Dr S Pushpakom
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

University of Reading School of Pharmacy
Are you ready to delve into the captivating world of molecular signaling and unravel the mysteries of the cardiovascular and nervous systems? We are thrilled to offer an exhilarating PhD opportunity at the forefront of scientific exploration. Read more
 Supervisors: Dr G Cottrell, Prof D Widera, Dr S Amadesi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
 Supervisors: Dr T Nasim, Prof C Wright
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more
 Supervisors: Dr T Nasim, Dr M Najafzadeh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more
 Supervisor: Dr T Nasim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of a personalized therapy for pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more
 Supervisor: Dr T Nasim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

The University of Manchester Faculty of Biology, Medicine and Health
A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
 Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more
 Supervisor: Dr T You
 1 August 2024  PhD Research Project  Self-Funded PhD Students Only
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Network-based predictive modelling of cardiovascular disease risk

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more
 Supervisor: Dr T You
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Interaction between innate immune activation and endothelial cells, linked to adverse cardiovascular events

University of Liverpool Institute of Systems, Molecular and Integrative Biology
The complement system is a key component of the immune response. Maintaining a balance between activation and inhibition of the complement system is key to preserving tissue homeostasis and enabling immune surveillance. Read more
 Supervisors: Dr N Liptrott, Dr R Rainbow, Prof C Dart
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterisation of a novel transporter for the atypical antipsychotic clozapine

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Schizophrenia is a severe psychiatric illness affecting about 24 million people worldwide. Schizophrenia can have a devastating effect on a patient’s life and is associated with increased mortality, with life expectancy reduced on average by 15 years compared to that of the general population. Read more
 Supervisors: Dr D Dickens, Prof M Pirmohamed
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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