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We have 4 Chemistry (mouse) PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Chemistry (mouse) PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 4 Chemistry (mouse) PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more

Studying protein homeostasis in healthy and malignant stem cell development

The Grey lab studies the role of protein homeostasis in healthy and malignant haematopoietic (blood) stem cell development. We focus on the proteome of healthy stem cells as they mature in vivo, expand in vitro and their therapeutic use for bone marrow transplantation. Read more

Self Funded PhD Project: Studies on the Design, Synthesis and Biological Evaluation of a Novel Bioactive Indane Scaffold

A wide range of bioactive indane based scaffolds are employed clinically as treatment of many disease states, including inflammatory [1], cancer [2] and neurological conditions [3] and also in the treatment of HIV [4]. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
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