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We have 6 Computational Chemistry (protein engineering) PhD Projects, Programmes & Scholarships

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Computational Chemistry (protein engineering) PhD Projects, Programmes & Scholarships

We have 6 Computational Chemistry (protein engineering) PhD Projects, Programmes & Scholarships

High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more

New Methods for modelling cofactor-dependent enzyme structure and function

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

Intracellular Capillarity of Biomolecular Condensates

The emerging role of biomolecular condensates formed through a liquid-liquid phase separation process inside biological cells is driving a paradigm change in our understanding of cellular organisation. Read more
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