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We have 21 Biophysics (structures) PhD Projects, Programmes & Scholarships

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Biophysics (structures) PhD Projects, Programmes & Scholarships

We have 21 Biophysics (structures) PhD Projects, Programmes & Scholarships

Untying the knot: Remodelling of G4 structures by the NER machinery- implications in human DNA repair and regulatory pathways

Open PhD position on Genome Stability and Biochemistry. Joint PhD scholarship - St Andrews and Bonn-Biology. Untying the knot. Remodelling of G4 structures by the NER machinery- implications in human DNA repair and regulatory pathways. Read more

The role of regulatory evolution in phage ecology

The regulation of genes crucially determines the fitness and function of all organisms. This is particularly relevant for bacteriophages, the viruses that infect bacteria, as they rely on a tightly scheduled program for a successful infection. Read more

Untangling how Shelterin safeguards telomere structure and stability - one molecule at a time

Background. Telomeres solve two problems with linear chromosomes. the end-replication problem, DNA loss from the end of chromosomes every replication cycle; and the end-protection problem, protection of the chromosome ends to prevent chromosome fusions. Read more

Seeing inside the brain of Alzheimer’s disease by cryoET

The aim of this PhD project is to determine the in situ 3D molecular structures associated with AD to understand disease mechanisms and molecular pathways that can lead to the rational design of a mechanism-based therapy. Read more

Understanding the evolution of gene regulatory networks through biophysical modelling and machine learning

The ability to coordinate the expression of genes within a cell is at the heart of life. When and how much of a specific gene is turned into a protein is essential for organisms to respond to their environment and to manage resources. Read more

Computational modelling to understand the key drivers of placental evolution

Supervisory Team. Bram Sengers (SoE), Rohan Lewis (Medicine). Project description. This project will use computational modelling in combination with 3D multiscale multimodal imaging to improve our understanding of placental evolution, in close collaboration between Engineering and Medicine. Read more

Probing Death Decisions from Morphogen Gradient Fields

Morphogen gradient scaling is one of the hottest fields in developmental biology at the moment. Scaling is fundamental, explaining how the machinery that controls pattern formation in development (the morphogens) can adapt, so that organs of different sizes show morphological structures which are proportioned. Read more

PhD in Chemistry - Multiphoton-induced single-molecule fluorescence of amino acids

Candidates are invited to apply for a PhD position in the Magennis research group in the School of Chemistry, which is available to start from 1st October 2024. The PhD project will develop and apply state-of-the-art single-molecule fluorescence techniques to study novel fluorescent amino acids. Read more

Regulation and mechanics in polarity

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

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