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Data Analysis (genes) PhD Projects, Programs & Scholarships

We have 13 Data Analysis (genes) PhD Projects, Programs & Scholarships

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  Application of data science to inherited genetic variants of apoptosis genes and susceptibility to breast cancer
  Prof A Cox, Dr K Walters
Applications accepted all year round

Funding Type

PhD Type

Background. The identification of the breast and ovarian cancer genes BRCA1 and BRCA2 two decades ago has resulted in both improved patient risk assessment and the use of PARP-inhibitors for treatment.
  Evolutionary genomic analysis of rodent immune genes
  Prof S Paterson, Prof M Viney
Applications accepted all year round

Funding Type

PhD Type

You will investigate how immune systems evolve. Immune systems are highly sophisticated networks encoded by hundreds of genes. One way to understand how these networks function is to compare them between related species, to see which genes are common between them and which are unique.
  Developing and applying computational methods to understand the genetics of ageing
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is the chief biomedical challenge of the 21st century, yet it remains a major puzzle of biology. Although it is clear that the process of ageing has a strong genetic component, much work remains to elucidate how the genome regulates ageing.
  Methods for quantitative genetic analyses in autotetraploids
  Prof Z Luo
Applications accepted all year round

Funding Type

PhD Type

Methods for quantitative genetic analysis have been well established in almost all important diploid plants and animal including humans, and have served as essential tools for dissecting the genetic architectures underlying agronomically, evolutionarily and medically interesting quantitative and complex traits.
  Using statistical and functional analysis to investigate the contrasting disease specific roles of IL6R and the chr17q12 locus in the development of rheumatoid arthritis and asthma
  Dr J Curtin, Prof A Simpson
Applications accepted all year round

Funding Type

PhD Type

The Arthritis Research UK and Respiratory Centres at the University of Manchester have extensive research programmes investigating the genetic components of rheumatoid arthritis (RA) and asthma.
  Genomic basis of extra-group paternity in the cooperatively breeding Seychelles warbler
  Dr H L Dugdale
Applications accepted all year round

Funding Type

PhD Type

Indirect genetic benefits are hypothesised to drive the evolution of extra-group paternity (EGP), yet its genomic basis is unknown.
  Tissue Engineering of Functional Cardiac Tissue using a Newly Characterised Cardiac Stem Cell Population
  Dr R Oldershaw, Dr R Barrett-Jolley, Dr A P Meeson
Applications accepted all year round

Funding Type

PhD Type

We will develop a novel route to create and test stem cell-derived engineered cardiac tissue for use in heart infarct repair or in vitro drug screening.
  Developing methods for the analysis of chromosome conformation data
  Dr T Thorne
Applications accepted all year round

Funding Type

PhD Type

Chromosome conformational data allows us to investigate the three dimensional structure of the genome. This project will involve developing novel computational and statistical methods for the analysis of genomic contact data.
  Developing pipelines for the inference of gene regulatory networks
  Dr T Thorne
Applications accepted all year round

Funding Type

PhD Type

Gene regulatory networks are fundamental to many processes that take place in the cell. However learning the structure of these networks from high-throughput experimental data and deriving useful biological insights is challenging.
  Bioinformatics analyses of unknown metagenomics fraction
  Dr S Gweon
Applications accepted all year round

Funding Type

PhD Type

"DNA sequencing technology now allows us to investigate not only the identity of organisms that are present in complex environments like soil, but also what these tiny microbes are doing.
  Bioinformatics studies of protein structures, functions and their interactions
  Dr L J McGuffin
Applications accepted all year round

Funding Type

PhD Type

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease.
  What is the impact of atypical neurogenesis on brain activity, cognition and behaviour?
  Dr A McNeill, Dr M Freeth
Applications accepted all year round

Funding Type

PhD Type

Neurogenesis is the process by which stem cells form brain cells. This process is disrupted by genetic mutations causing childhood neurological disorders which cause symptoms such as learning disability, behaviour problems and epilepsy.
  Discovery and characterisation of new antibiotics from uncultivated microbes.
  Dr J Owen
Applications accepted all year round

Funding Type

PhD Type

Recent developments in DNA sequencing technology have greatly enriched our understanding of the microbial world. By directly sequencing DNA extracted from communities of environmental microbes, we have been able to observe a hidden majority of microbial species that cannot be readily grown in the laboratory.
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