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University of Sheffield, Department of Biomedical Science PhD Projects, Programs & Scholarships

We have 21 University of Sheffield, Department of Biomedical Science PhD Projects, Programs & Scholarships

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  Assessment of excitability of Human pain neurons pain neurons using a novel calcium imaging assay
  Dr M Nassar
Applications accepted all year round

Funding Type

PhD Type

Pain is an important warning system to guard against tissue damage. Pathological pain, however, has no warning value and has huge economical, social and personal costs on society.
  Cell plasticity in development and disease
  Dr K Campbell
Applications accepted all year round

Funding Type

PhD Type

Although 90% of cancer deaths are caused by metastasis, the underlying pathogenic mechanisms are poorly understood.
  Defining the dynamics of lineage segregations during human neuromesodermal axial progenitor differentiation
  Dr A Tsakiridis, Dr A Fletcher
Applications accepted all year round

Funding Type

PhD Type

Embryonic axis elongation is the process that gives rise to all cell types making up the body trunk.
  Developing a therapy for hearing loss using human pluripotent stem cells
  Prof M Rivolta
Applications accepted all year round

Funding Type

PhD Type

The vast majority of cases of deafness are produced by the irreversible loss of the sensory hair cells and their associated neurons.
  Elucidating the molecular function of SNAP29 a gene mutated in CEDNIK syndrome
  Dr A Peden
Applications accepted all year round

Funding Type

PhD Type

CEDNIK (cerebral dysgenesis, neuropathy, ichthyosis and keratoderma) syndrome is a rare fatal disease caused by the loss of SNAP29.
  Elucidating the signalling pathways important for plasma cell biology and antibody secretion
  Dr A Peden, Dr M Collins
Applications accepted all year round

Funding Type

PhD Type

Plasma cells are the antibody secreting cells of the immune system thus are vital for fighting infection. However, dysregulation of plasma cell function is linked to a broad range of disease from Lupus to multiple myeloma.
  Engineering the skeletal muscle stem cell niche using microporous tissue engineering constructs
  Dr A G Borycki
Applications accepted all year round

Funding Type

PhD Type

Background. Satellite cells are skeletal muscle stem cells that reside in a specific micro-environment called the niche and are responsible for muscle repair upon injury or diseases.
  Homeostatic balancing of neuronal excitation and inhibition in vivo
  Dr A Lin
Applications accepted all year round

Funding Type

PhD Type

Neuronal excitation and inhibition are very carefully balanced in the brain, and perturbed excitation/inhibition (E/I) balance has been linked to diseases such as epilepsy, autism and schizophrenia.
  Identification of the molecular pathways that guide zebrafish regeneration.
  Dr H Roehl
Applications accepted all year round

Funding Type

PhD Type

The study of regenerative biology aims to elucidate the innate ability of organisms to replace tissues or organs after they have been removed or damaged.
  Imaging neurotransmitter release to measure synaptic plasticity underlying associative memory
  Dr A Lin
Applications accepted all year round

Funding Type

PhD Type

How does the brain encode memories? We think learning occurs by changes in the strength of synaptic connections between neurons, but the precise mechanisms by which this synaptic plasticity occurs is often unknown.
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