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University of Sheffield, Department of Biomedical Science PhD Projects, Programs & Scholarships

We have 22 University of Sheffield, Department of Biomedical Science PhD Projects, Programs & Scholarships

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  Assessment of excitability of Human pain neurons pain neurons using a novel calcium imaging assay
  Dr M Nassar
Applications accepted all year round
Pain is an important warning system to guard against tissue damage. Pathological pain, however, has no warning value and has huge economical, social and personal costs on society.
  Cell plasticity in development and disease
  Dr K Campbell
Applications accepted all year round
Although 90% of cancer deaths are caused by metastasis, the underlying pathogenic mechanisms are poorly understood.
  Deciphering Roles of SUMOylation in mini-Human Brains in Health and Disease
  Dr C Guo, Dr S Brown
Applications accepted all year round
Neurodegenerative disorders and cerebral ischemia are incurable conditions, imposing tough medical challenges and a substantial economic burden on health services.
  Defining the dynamics of lineage segregations during human neuromesodermal axial progenitor differentiation
  Dr A Tsakiridis, Dr A Fletcher
Applications accepted all year round
Embryonic axis elongation is the process that gives rise to all cell types making up the body trunk.
  Developing a therapy for hearing loss using human pluripotent stem cells
  Prof M Rivolta
Applications accepted all year round
The vast majority of cases of deafness are produced by the irreversible loss of the sensory hair cells and their associated neurons.
  Elucidating the molecular function of SNAP29 a gene mutated in CEDNIK syndrome
  Dr A Peden
Applications accepted all year round
CEDNIK (cerebral dysgenesis, neuropathy, ichthyosis and keratoderma) syndrome is a rare fatal disease caused by the loss of SNAP29.
  Elucidating the signalling pathways important for plasma cell biology and antibody secretion
  Dr A Peden, Dr M Collins
Applications accepted all year round
Plasma cells are the antibody secreting cells of the immune system thus are vital for fighting infection. However, dysregulation of plasma cell function is linked to a broad range of disease from Lupus to multiple myeloma.
  Engineering the skeletal muscle stem cell niche using microporous tissue engineering constructs
  Dr A G Borycki
Applications accepted all year round
Background. Satellite cells are skeletal muscle stem cells that reside in a specific micro-environment called the niche and are responsible for muscle repair upon injury or diseases.
  Homeostatic balancing of neuronal excitation and inhibition in vivo
  Dr A Lin
Applications accepted all year round
Neuronal excitation and inhibition are very carefully balanced in the brain, and perturbed excitation/inhibition (E/I) balance has been linked to diseases such as epilepsy, autism and schizophrenia.
  Identifying new drugs to combat the virulence mechanisms underlying multidrug-resistant typhoid.
  Dr D Humphreys
Applications accepted all year round
Multidrug-resistant typhoid. --------------------------------------------. The world is facing an epidemic of multidrug-resistant (MDR) typhoid fever.
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