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The University of Manchester, Department of Chemistry PhD Projects, Programmes & Scholarships
We have 20 The University of Manchester, Department of Chemistry PhD Projects, Programmes & Scholarships
We have 20 The University of Manchester, Department of Chemistry PhD Projects, Programmes & Scholarships
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Mechanochemistry with mechanical bonds
Any force developed at the macroscopic scale can induce dramatic changes at the molecular scale, even breaking covalent bonds.[1] Indeed, mechanical force is a formidable source of energy that, with its ability to distort, bend and stretch chemical bonds, is unique in its ability to promote reaction pathways that are otherwise inaccessible to traditional methods of activation. Read more
Development of new retrosynthetic disconnections through radical-nucleophilic substitution
Background. Nucleophilic substitution is arguably the most important class of reaction in organic synthesis. Indeed, these reactions are used every day to synthesise new pharmaceuticals, agrochemicals, polymers and natural products. Read more
Flexible Peptide Decorated Polyaminocarboxylate Ligands for Selective Extraction of Radiotherapeutic Metals for Targeted Alpha Cancer Therapy
Nuclear fission produces radioactive isotopes with decay products encompassing a large proportion of the Periodic Table. Many of these isotopes are considered as waste and are currently disposed of following separation. Read more
Molecular editing of complex molecules via photocatalytic heteroatom insertion and migration
Modern approaches to drug discovery are increasingly impacted by the development of new synthetic methods, specifically the step-economical and chemospecific manipulation of late-stage intermediates. Read more
Development of New Materials for Optically Programmable and Re-Programmable Printable Memristors for Neuromorphic Computing
Printed electronics (i.e. the technology of fabricating electronic devices and circuits using additive, low-temperature printing processes) promises low-cost, on-demand electronic circuit fabrication, in new form-factors (e.g. Read more
Sustainable production of advanced synthetic fuels: innovative solutions using metabolic engineering, scaled fermentation and chemical processing
The development of biological routes towards advanced synthetic fuels (biofuels) addresses the challenge of reducing fossil fuel usage and is a step forward in accelerating the growth of the bioeconomy. Read more
Molecular Design for the Energy Harvesting Materials
Energy is one of many global challenges for our modern society. Lighting devices based on the Organic Light-emitting Diodes (OLEDs) could answer this global challenge by offering the products with energy efficiency up to 100%. Read more
Computational f Element Chemistry
Research in the Kaltsoyannis group focuses on the computational determination of the electronic structure and bonding in molecules and solids from all areas of the periodic table, with particular emphasis on compounds of the f elements. Read more
The chemistry and biophysics of phosphoryl transfer enzymes
One of the most remarkable features of the chemistry of living organisms is the evolutionary utilisation of phosphate esters to provide biopolymers that encode genetic information, deliver temporal protein regulation, generate and distribute free energy throughout the cell, and to provide a ubiquitous handle for metabolic intermediates. Read more
Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics
Plastics are a broad range of solid polymeric materials that have found widespread application as industrial components and consumer goods. Read more
New NMR methods for complex mixture analysis
Applications are invited from students with independent funding for PhD research in the development and application of novel methods in NMR spectroscopy. Read more
Modelling photosynthetic water oxidation
This project aims use molecular modelling methods and spectroscopy to understand how the protein environment of electron transfer cofactors in photosysnthesis and in particular how the water oxidising complex, facilitates electron transfer and also helps stabilise these radical species to maintain a charge separated state. Read more
Method development and applications of Electron Paramagnetic Resonance (EPR)
Electron Paramagnetic Resonance (EPR) is a spectroscopic tool used to study systems containing unpaired electrons. EPR has wide ranging applications from materials science and quantum computing to structural biology and (bio)catalysis. Read more
Engineering synthetic ribosomal RNAs (rRNAs) in yeast
Advances in DNA synthesis technology have led to rapid growth in the field of synthetic biology, heralding a nascent era of synthetic genomics. Read more
Design, Synthesis and Biological Evaluation of Novel Analogues of the Bioactive Natural Products, Incarviditone and Incarvilleatone
The polyclic natural products incarviditone and incarvilleatone have recently attracted attention due to their synthetically challenging structures as well as their interesting biological properties. Read more
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