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We have 14 University of Leicester, Department of Genetics and Genome Biology PhD Projects, Programmes & Scholarships

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Department of Genetics and Genome Biology  University of Leicester

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University of Leicester, Department of Genetics and Genome Biology PhD Projects, Programmes & Scholarships

We have 14 University of Leicester, Department of Genetics and Genome Biology PhD Projects, Programmes & Scholarships

Epigenetic ageing and calorie restriction in an insect model system

This project will help establish an insect model for epigenetic ageing, by analysing the effects of calorie restriction on chronological and epigenetic aging in an important insect model, Nasonia vitripennis, extending our discovery of an epigenetic clock in Nasonia. . Read more

Investigating the role of SUMOylation in meiotic recombination and chromosome segregation in Arabidopsis

Post-translational modifications of proteins such as phosphorylation, methylation and acetylation have been extensively studied in eukaryotes and now the Small Ubiquitin modifier (SUMO) is gaining attention for its importance in fundamental biological roles. Read more

Unlocking the genetic potential of barley by modulating recombination

Barley is a major worldwide crop used for malting and animal feed. However, breeding new varieties is constrained by the frequency of genetic crossovers (1-3 crossovers per chromosome pair) and their distribution (biased towards the chromosome ends) that underpin crop improvement1,2. Read more

Enhancing meiotic recombination in wheat by modulating RECQ helicases

Wheat accounts for 20% of the calories and protein consumed by humans and is the largest crop in the UK, but yields have plateaued and are susceptible to decline due to extreme weather conditions. Read more

The Evolution of Vision in Mosquitoes

Background . Due to their capacity to transmit viruses such as Zika and parasites like Plasmodium (the causative agent of malaria), mosquitos are regarded by the World Health Organization as one of the most lethal organisms on our planet (WHO | Global vector control response 2017–2030, 2020). Read more

Identifying the neurogenetic network underlying visually-driven sleep

General background. Sleep is a behavioural quiescence widely observed in the animal kingdom. During sleep, an animal’s motor activity, as well as their responsiveness to environmental stimuli, are largely reduced. Read more

Early life environment changes how organisms age.

This project will help understand why organisms age differently by establishing the effect of early life environments on epigenetic ageing in the model insect, Nasonia vitripennis. Read more

Genomics of malignant pleural mesothelioma

Malignant pleural mesothelioma is a rare, incurable cancer that carries a dismal prognosis. Its incidence is increasing globally despite its primary cause, asbestos exposure, having been known for over 50 years. Read more

Exploiting raptor genome sequences to combat wildlife crime

Birds of prey have suffered persecution for centuries through trapping, shooting, poisoning and theft from the wild to meet the demand from egg collectors and falconers; they were also amongst the earliest beneficiaries of DNA testing in wildlife forensics. Read more

Understanding the role of mucin genetic variation in lung disease

  Research Group: Human & Medical Genetics
Understanding how genetic variation contributes to lung diseases is important in understanding how the disease develops and identifying potential molecular targets for therapy. Read more
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