University of Sheffield, Department of Infection, Immunity and Cardiovascular Disease PhD Projects, Programs & Scholarships

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Atherosclerosis is a leading cause of death in the UK. It is characterized by the build-up of fatty plaques in arteries. Some plaques are stable whereas others develop into dangerous forms that are vulnerable to rupture, an event that causes heart attack and stroke.

Bacterial iron uptake pathways as targets for the development of novel antimicrobials

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Dr M Thomas

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Antimicrobial resistance is an ever increasing problem. Presently it is estimated to be responsible for 700,000 deaths p.a. and it is predicted that this figure will rise to 10 million by 2050.

Characterisation of bacterial effectors delivered by the type VI secretion system

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Dr M Thomas

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Many pathogenic bacteria secrete protein ’effectors’ that benefit the pathogen by allowing it to subvert, damage or kill the host.

Defining strategies to promote immunity to multi-drug resistant Staphylococcus aureus.

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Dr L Prince

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Staphylococcus aureus is a highly successful pathogen that can circumvent many aspects of immunity. White blood cells, including neutrophils, are a critical defence against infection and yet S.

How does cytokine signalling cause kidney hyperplasia?

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Dr M Fragiadaki, Prof J Sayers

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic kidney disorder, with more than 12 million people are affected worldwide.

How to eat big, small and irregular: Force generation in phagocytic immune cells

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Dr S Johnston, Dr R Hawkins

Application Deadline: 29 January 2020

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

Phagocytosis (eating) of microbes, dead cells and particulates by immune cells is critical for health and protecting against disease.

Identifying inhibitors specific to the OPG-kinome: towards novel treatments for Pulmonary Arterial Hypertension (PAH).

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Prof A Lawrie, Dr R Thompson

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Background. Pulmonary arterial hypertension (PAH) is a fatal progressive disease. Median life expectancy in untreated PAH patients is 2.8 years.

Machine Learning Methods for Behaviour Analysis in Cardiovascular Disease

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Prof T Chico, Prof L Mihaylova

Application Deadline: 29 January 2020

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

Cardiovascular diseases affect patient’s day-to-day activities by causing symptoms such as breathlessness on exertion but there is no effective way to measure this.

Optogenetic programming of inflammation - in vivo Opto-GPCR approaches in neutrophils.

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Prof S Renshaw, Prof A Condliffe

Application Deadline: 29 January 2020

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

White blood cells called neutrophils have a powerful protective role and without them we develop overwhelming infection, yet they are also directly responsible for the tissue damage that characterises many common inflammatory diseases.

Project title: Elucidating the mechanisms of pathology in neurodevelopmental white matter diseases

University of Sheffield
Department of Infection, Immunity and Cardiovascular Disease

Dr N Hamilton

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Our research interest is to dissect the mechanism of auto-inflammatory neurological disorders using zebrafish as an animal model.