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Dundee×
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Cancer / Oncology PhD Projects, Programs & Scholarships in Dundee

We have 11 Cancer / Oncology PhD Projects, Programs & Scholarships in Dundee

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  Medical Research Council (MRC) Cancer and Genome Integrity PhD Programme 2019
Defects in DNA replication or DNA repair can lead to mutations and other genomic alterations that give rise to cancers, and consequently tumours tend to have a high degree of genome instability.
  Enabling Precision Medicine through Oesophageal Cancer Proteogenomics
  Prof R Petty, Prof A I Lamond
Applications accepted all year round
Capitalising on technological advances in next generation sequencing, genomic landscaping projects have provided a comprehensive catalogue of genetic abnormalities in human cancer, and in some tumour types provided classifications useful for clinical decision making.
  Quantitative proteomic and cell biological analysis of TGF driven tumour promotion in melanoma and squamous cell cancers
  Dr G J Inman, Prof A I Lamond
Applications accepted all year round
Transforming growth factor- can act as both a potent tumour suppressor and tumour promoter in a context dependent manner.
  Precision Medicine for Squamous cell Carcinomas – NRF2/KEAP1 subtypes
  Prof A Dinkova-Kostova, Dr C Proby, Prof R Petty
Applications accepted all year round
Squamous cell carcinomas (SCCs), which arise at a variety of anatomical sites from stratified squamous epithelium, represent the most frequent human solid malignancies and are a major cause of cancer mortality.
  DNA Strategic Epigenetic Biomarkers in Melanoma
  Dr C Proby, Prof C N A Palmer
Applications accepted all year round
Hypothesis. That tumour-specific DNA methylation present in free circulating DNA from melanoma patients will enable early detection of disease relapse or metastasis facilitating life-preserving benefit from additional therapies such as immune checkpoint inhibitors.
  Precision Medicine: Using machine learning and classification methods to identify immune evasion signatures in high-risk malignancies
  Dr C Proby, Prof R Petty
Applications accepted all year round
Squamous cell carcinomas across multiple sites (lung, head and neck, skin, oesophagus) represent the most frequent human malignancies and are a major cause of cancer mortality with limited therapeutic options for advanced disease.
  Investigating phosphorylation-dephosphorylation dynamics during the cell cycle.
  Dr A Saurin
Applications accepted all year round
Protein phosphorylation is a critical post-translational modification needed for most biological responses. Although we have currently identified hundreds of thousands of different phosphorylation sites, we still lack one fundamental piece of information that is common to every single one of those sites.
  Establishing the potential of GSK3 manipulation for the treatment of human leukaemias
  Dr C Sutherland, Dr S Tauro
Applications accepted all year round
Background. Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world.
  Targeting the Achilles’ heel – dissecting drug resistance in ovarian cancer
  Dr G Smith, Dr M Ferguson
Applications accepted all year round
Ovarian cancer, the most common cause of gynaecological cancer death, is frequently diagnosed when the disease is already advanced, when surgery is not always possible.
  A strategy to kill cancer cells by inducing proteotoxic stress
  Dr Y Kulathu
Application Deadline: 31 March 2019
University of Dundee, MRC Protein Phosphorylation and Ubiquitylation Unit, Dundee, United Kingdom. Dr. Yogesh Kulathu. Cancer cells are heavily reliant on their ubiquitin proteasome system (UPS) to maintain proteostasis and cell survival.
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