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Cell Biology / Development PhD Projects, Programs & Scholarships in Dundee

We have 19 Cell Biology / Development PhD Projects, Programs & Scholarships in Dundee

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Biological & Medical Sciences

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Dundee  United Kingdom

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We have 19 Cell Biology / Development PhD Projects, Programs & Scholarships in Dundee

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Molecular mechanisms underlying Parkinson's disease

There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more

EASTBIO: Your Best Face Forward - how cereals regulate their epidermal surfaces

Plants living on land face brutal conditions with threats from pests, dehydration and temperature extremes. To survive and thrive on land, plants evolved a specialised surface, sealed by a waxy ‘cuticle’ and distinctive epidermal cells such as gas pores and defensive barbs. Read more

Wellcome Integrated Molecular, Cellular and Translational Biology PhD Training Programme

The Wellcome Trust Integrated molecular, cellular and translational biology programme combines scientific excellence with a commitment to improving the working environment and transition support for trainees. Read more

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Regulation and mechanics in polarity

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Is there a Role for Activated Akt in Palatogenesis?

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Development of micro-incubator OCT/ OCE bioreactor system to engineer a robust musculoskeletal tissue model

Achieving adequate musculoskeletal tissue healing is one of the most challenging factors in the repair of orthopaedic tissues. The problem of hard-to-soft tissue fixation is the major cause of failure of replacement grafts and leads to further musculoskeletal degeneration e.g. Read more

Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c

The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more

Interdisciplinary investigation of the role of amino acids in immunometabolic responses to metformin in human cells

There is overwhelming evidence that inflammation contributes to the development of cardiovascular disease (CVD) but counterbalancing this is evidence from meta-analysis of randomised control trials that many existing anti-inflammatory drugs, such as COX2 inhibitors and anti-TNF drugs, tend if anything to exacerbate risk of CVD. Read more

EASTBIO: How cells prevent errors in chromosome inheritance during cell division

Human cells store their genetic information in 46 chromosomes. To maintain this vital genetic information, a complete set of chromosomes must be inherited precisely by each daughter cell after cell division. Read more

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