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We have 18 Developmental Biology PhD Projects, Programmes & Scholarships in Dundee
Developmental Biology PhD Projects, Programmes & Scholarships in Dundee
We have 18 Developmental Biology PhD Projects, Programmes & Scholarships in Dundee
Characterisation of the impact of NICD S2513 mutation on human segmentation using iPS derived somitoids
During early development cells differentiate into the different cell types required to form the tissues that make up the embryo. Research into human embryological development is challenging for practical and ethical reasons. Read more
MSc by Research: Computational Evolutionary Transcriptomics for Cancer Diagnostics
In this computational Master project, we will consult new transcriptomic evidence from bulk- and single cells (single-cell genomics) to test whether evolutionary information of gene birth events within the tree of life can be harnessed to inform transcriptomic signatures for cancer type diagnostics (evolutionary transcriptomics). . Read more
MSc by Research: DNA Replication Coupled Mechanisms that control cell fate transitions
DNA replication is required for successful cell fate transitions across diverse physiological, experimental, and pathological contexts, involving factors often deregulated in human cancer and intellectual disabilities. Read more
MSc by Research: Understanding the contribution of natural variation in upstream open reading frames to plant climate adaptation
In our warming climate, understanding how plants respond to elevated temperatures is vital for breeding temperature-resilient crops. Read more
MSc by Research: Regulation of Kinetochore function by PLK1
Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy and it is a hallmark of cancer, while in oocytes represents the major source of miscarriages and genetic disease. Read more
MSc by Research: Caenorhabditis elegans: A genetic model to study anosmia, loss of olfaction, associated with Parkinson’s Disease
Parkinson’s Disease or PD is the second fastest growing neurodegenerative disease in the UK. PD is an age-associated disease characterized by tremors, change in gait, loss of appetite and loss or reduction in the sense of smell (anosmia). Read more
MSc by Research: Analysis of the involvement of mechanosensory system in food search and feeding behaviour
Animals rely on their sensory system to find food and avoid predators. Although olfaction and gustation have been well studied, effect of mechanosensation on food search is underexplored although touch is used frequently in human infants. Read more
MSc by Research: Investigation of the interplay between the cell cycle and Notch intracellular domain levels in presomitic mesoderm cells in somitogenesis
One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more
MSc by Research: Function of presomitic mesoderm specific phosphorylation of the Notch intracellular domain in somitogenesis
The Notch signalling pathway is one of the key pathways required for the developing embryo. It is especially important for the process of somitogenesis, the formation of body segments that develop into e.g. Read more
MSc by Research: Deciphering the role(s) of Cdk1 during oocyte meiosis
Meiosis is a specialised type of cell division that produces haploid daughter cells known as gametes that are important for sexual reproduction. Read more
MSc by Research: m6A modification of segmentation clock mRNAs and its role in somitogenesis
During early embryogenesis, segments (somites) are formed during a process called somitogenesis. These somites will go on to form the bones and muscles of the skeleton. Read more
MSc by Research: How does Dysregulated Protein Kinase Signalling Cause Human Neurodevelopmental Disorders?
The overarching goal of this project is to identify and characterise protein kinase signalling pathways that are disrupted in human neurodevelopmental disorders. Read more
MSc by Research: Regulation and mechanics in polarized trafficking
Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more
MSc by Research: Post transcriptional control of the segmentation clock and somitogenesis
During early embryogenesis, segments (somites) are formed during a process called somitogenesis. These somites will go on to form the bones and muscles of the skeleton. Read more
MSc by Research: Monitoring and manipulating kinase activity in stem cells
Posttranslational modifications of proteins are important regulatory events that impact most if not all physiological functions of cells. Read more
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