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We have 25 Genetics PhD Projects, Programmes & Scholarships in Dundee

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Biological Sciences

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Dundee  United Kingdom

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Genetics PhD Projects, Programmes & Scholarships in Dundee

We have 25 Genetics PhD Projects, Programmes & Scholarships in Dundee

Using chemical-genetics to inhibit and characterise “undruggable” enzymes

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

MSc by Research: The Generation Gap – understanding tissue communication during grain development

Cereal grain provides more calories than any other source to our diet, making grain production vital to food security. We study grain development in barley, a globally important cereal, and a powerful genetic model system. Read more

MSc by Research: Signaling pathways controlling epidermal development in cereals

Plants living on land face brutal threats from pests, dehydration and temperature. To survive and thrive, land plants evolved a waxy ‘cuticle’ and distinctive epidermal cells such as gas pores and defensive barbs. Read more

MSc by Research: ADP-ribosylation in dementia and motor neuron disease

ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

MSc by Research: Jasmonate control of barley development

From the earliest farmers to modern plant breeders, humans have continually modified the body plan of cereals, sometimes drastically, to generate higher grain yields. Read more

MSc by Research: Regulation of Architecture in Barley

Plant architecture, or body plan, plays a key role in determining grain yield of crop plants. However, we have little understanding of the molecular genetic basis of architecture in the temperate cereals such as barley (Hordeum vulgare L.), especially in comparison to the warm weather crops such as rice (Oryza sativa). Read more

MSc by Research: Function of presomitic mesoderm specific phosphorylation of the Notch intracellular domain in somitogenesis

The Notch signalling pathway is one of the key pathways required for the developing embryo. It is especially important for the process of somitogenesis, the formation of body segments that develop into e.g. Read more

MSc by Research: Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus

Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more

MSc by Research: Investigating the tumor suppressor functions of chromatin remodelling

One of the unanticipated outcomes of population based genome sequencing has been the finding that genes involved in the regulation of many genes are mutated at high frequency in tissue specific cancers. Read more

MSc by Research: Genetic interactions and novel genes that regulate lignin biosynthesis and straw quality in barley

Lignin is a major component of plant cell walls, and has a significant influence on the digestibility and uses of plant biomass. The lignin biosynthesis pathway has been one of the most intensively studied. Read more

MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

MSc by Research: How are SUMO substrates selected for modification ?

SUMO has diverse roles in cellular physiology that in most cases are mediated by its ability to interact non-covalently with hydrophobic patches of low sequence complexity known as SUMO Interaction Motifs (SIMs). Read more

School of Life Sciences Black Scholars Programme

The School of Life Sciences and the University of Dundee are committed to addressing under-representation in postgraduate research and we are pleased to offer our first Masters by Research Scholarships for UK students from Black or Black-Mixed Backgrounds. Read more
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