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We have 9 Pharmacology PhD Projects, Programmes & Scholarships in Dundee
Pharmacology PhD Projects, Programmes & Scholarships in Dundee
We have 9 Pharmacology PhD Projects, Programmes & Scholarships in Dundee
Investigation of short-term effects of colchicine on blood proteins using proteomics
The anti-inflammatory medication colchicine has been shown to significantly improve cardiovascular outcomes post heart attack and in chronic heart disease patient groups, suggesting it may be a suitable candidate for repurposing in cardiovascular diseases. Read more
Lessening Health Inequalities in Type 2 Diabetes Through Innovative Drug Repurposing
Most older type 2 diabetes (T2D) drugs were developed through pre-clinical studies and then trials that model T2D as it is experienced by older white people (1). Read more
Vascularisation of tumour organoids for mechanistic and drug development
Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more
Investigating how dormant senescent cells can drive drug-resistance following chemotherapy
Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more
Using chemical-genetics to inhibit and characterise “undruggable” enzymes
The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more
Investigations into the protective actions of CBD in the early synaptic deficits in dementia.
Accumulation of hyper-phosphorylated tau is a key event in Alzheimer’s disease (AD). Aberrant changes in tau cause synaptic abnormalities and cognitive deficits in early AD. Read more
Evaluating the therapeutic potential of leptin-based hexamers in neurodegenerative disease
Translation of basic research into Alzheimer’s disease (AD) therapies is hindered by our inability to turn promising lab results into drugs that can be taken by patients. Read more
MSc by Research: Molecular characterisation of the factors driving lung fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function. At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more
MSc by Research: Glueing proteins together with small molecules
Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
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