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Genetics PhD Projects, Programs & Scholarships in Edinburgh

We have 101 Genetics PhD Projects, Programs & Scholarships in Edinburgh

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  MRC four-year PhD programme in Human Genetics, Genomics and Disease

Funding Type

PhD Type

Applications are invited from outstanding candidates to join an MRC funded 4-year multi-disciplinary PhD programme in Human Genetics, Genomics and Disease at the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
  Precision Medicine DTP - Dynamic changes that protect oocytes from chromosome mis-segregation
  Research Group: Institute of Cell Biology
  Prof H Ohkura, Dr T Ly, Dr A Kouznetsova
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Before fertilisation, oocytes arrest in metaphase in humans, as well as many other animal species including mouse and Drosophila.
  Precision Medicine DTP - Investigating the contribution of rare genetic variants to depression
  Research Group: Institute of Evolutionary Biology
  Dr S Knott, Dr P Navarro, Prof C Haley
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Genome-wide association studies (GWAS) are revealing the role of common genetic variants in the control of diseases and underlying traits.
  Precision Medicine DTP - Dissecting the biophysics of ocular transcription factors in vivo
  Dr D Papadopoulos, Prof W Bickmore, Prof V Vukojevic
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Of the ~1,600 human TF genes, up to ~25% (~400 genes) are expected to be haploinsufficient with a plethora of them leading to developmental disorders1, underlining that transcription factor (TF) abundance (dosage) plays a major role during cell and tissue specification.
  Precision Medicine DTP - Leveraging protein quantitative trait loci to discover new biology and therapeutic targets
  Prof J Wilson, Dr P Navarro, Dr L Klaric
Application Deadline: 8 January 2020

Funding Type

PhD Type

Proteins circulating in blood are derived from multiple organs and cell types, and consist of both actively secreted and passively leaked proteins.
  Precision Medicine DTP - How do IFITM proteins regulate the Interferon Related DNA-damage Resistance Signature (IRDS) and clinical outcomes in cancers of high unmet clinical need?
  Dr R Sloan, Prof K Ball, Dr S Wilson
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Interferon Induced Transmembrane proteins (IFITMs) are a family of innate immune membrane proteins that can inhibit viral infection at cell entry (e.g.
  Precision Medicine DTP - Genomic analysis of the impact of sexual recombination on the segregation of virulence genes in African trypanosomes
  Research Group: The Roslin Institute
  Dr L Morrison, Dr A MacLeod, Dr J Prendergast
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. African trypanosomes are vector-borne protozoa that cause serious human and animal disease across sub-Saharan Africa.
  Precision Medicine DTP - Omics Prediction of Incident Disease
  Research Group: Centre of Genomic and Experimental Medicine
  Dr R Marioni, Dr C Hayward, Dr C Vallejos
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Disease prediction years prior to onset is a major goal for biomedical research. This may be possible through the development of cutting edge statistical and machine learning tools and their application to millions of biological data points from thousands of individuals.
  Wellcome Trust funded four-year PhD programme in ‘One Health Models of Disease: Science, Ethics and Society’

Funding Type

PhD Type

Edinburgh Infectious Diseases, with the Centre for Biomedicine, Self and Society, is delighted to open applications to the first cohort of students on this new Wellcome Trust funded four-year PhD programme.
  Precision Medicine DTP - Illuminating roles of Wnt/b-Catenin signalling in nonalcoholic fatty liver disease (NAFLD)
  Research Group: MRC Centre for Regenerative Medicine
  Dr K Kaji, Dr S Tomlinson, Dr J Fallowfield
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Non-Alcoholic Fatty Liver Disease (NAFLD) caused by a high fat diet (HFD) is a growing major public health problem world-wide.
  Precision Medicine DTP - Taming the Hippo in mesothelioma through proteogenomics
  Dr C G Hansen, Prof J Lehtio
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Pleural Mesothelioma is an asbestos-related cancer, which originates in the pleural lining of the lung and is characterized by a diverse phenotype.
  Precision Medicine DTP – Investigating the metabolic alterations that initiate pre-neoplastic development in zebrafish and in humans
  Research Group: Centre for Inflammation Research
  Dr Y Feng, Dr K Burgess, Dr R Burchmore, Dr G Ho
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. “Warburg metabolism” is characterised by an increased uptake of glucose and its conversion to lactate by glycolysis under normoxia.
  Precision Medicine DTP – Using Omics to Understand the Genes and Pathways Underlying Alcohol Use Disorder
  Research Group: Centre of Genomic and Experimental Medicine
  Dr K Evans, Dr T-K Clarke, Dr S Glerup
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Alcohol use disorder (AUD) is a chronic relapsing brain disease characterised by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional state when not using alcohol.
  Precision Medicine DTP – Integration of single-cell RNA sequencing data from human and murine kidney disease to identify novel therapeutic targets
  Dr BC Conway, Dr T Chandra, Dr D Ferenbach
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Chronic kidney disease (CKD) is a major risk factor for cardiovascular disease and for end-stage kidney disease (ESRD), at which point patients require dialysis or transplantation.
  Precision Medicine DTP – Development of clinically relevant models of undifferentiated pleomorphic sarcoma using a genetic screening approach
  Research Group: Edinburgh Cancer Research Centre
  Prof V Brunton, Dr L Boulter, Dr M Taylor, Prof D M Salter
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Sarcomas are relatively uncommon cancers thought to arise from pluripotent mesenchymal stem cells. Undifferentiated pleomorphic soft tissue sarcoma (UPS), though one of the commonest sarcoma subtypes encountered, exemplify the limitations of historical progress in sarcoma therapy.
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