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Endocrinology (metabolism) PhD Projects, Programs & Scholarships

We have 32 Endocrinology (metabolism) PhD Projects, Programs & Scholarships

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We have 32 Endocrinology (metabolism) PhD Projects, Programs & Scholarships

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Targeting steroid metabolism to block colorectal cancer proliferation

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds. Read more

PhD student position available in macronutrition and signaling regulated RNA metabolism

PhD student position available in macronutrition and signaling  regulated RNA metabolism. The main research focus of our laboratory is to understand the participation of RNA processing in the regulation of energy metabolism in the context of obesity and diabetes. . Read more

Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism

24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g. Read more

The role of glucocorticoid desulfation in chronic inflammatory disease pathophysiology

Chronic inflammatory diseases (CIDs) are a common group of highly disabling immune conditions leading to persistent inflammation and tissue-specific manifestations, such as ulcerative colitis and arthritis. Read more

Intracrine GPCRs as master regulators of adipocyte lipolysis and metabolic disease

This project, funded through the MRC Advanced Inter-disciplinary Models Doctoral Training Partnership (AIM DTP), aims at investigating a new emerging paradigm in G protein-coupled receptor (GPCR) signalling in the control of adipocyte metabolism and its implications for the pharmacological therapy of metabolic disease. Read more

Circadian clock control of adipocyte metabolism

Obesity is a major public health issue affecting one third of UK adults, and an estimated 2.1 billion individuals worldwide. The role of circadian clock dysfunction in the development of obesity is becoming clear, with disruptive lifestyles (e.g. Read more

Enhancing clinical metabolomic studies through improved laboratory and bioinformatics tools

Applications will be reviewed until a suitable candidate is appointed and funding is available. Metabolites play many important roles in humans including in metabolism of food, synthesis of proteins and DNA, in signalling and regulation of biochemical mechanisms and in the development and progression of diseases. Read more

RNA-therapeutic approaches for metabolic pathologies

  Research Group: Metabolism & Gene Regulation
Analysis of the proteome and transcriptome has demonstrated the existence of a far greater transcriptomic complexity than previously catalogued. Read more

Deciphering the role of white and brown adipocytes in metabolic disease

Our work focuses on understanding how obesity drives the development of type 2 diabetes and cardiovascular disease. Specifically, it aims to decipher molecular determinants of adipocyte number and distribution within the body; key factors of susceptibility to obesity-associated cardiometabolic diseases. Read more

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