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Endocrinology (metabolism) PhD Projects, Programs & Scholarships

We have 20 Endocrinology (metabolism) PhD Projects, Programs & Scholarships

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Showing 1 to 15 of 20
  Targeting the Role of Myeloid Steroid Metabolism in Chronic Inflammation
  Dr R Hardy, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Rhythmic control of energy balance - to understand how our internal clocks regulate energy metabolism
  Dr D Bechtold, Prof D Ray
Applications accepted all year round

Funding Type

PhD Type

24-hour rhythms are present in virtually all aspects of our behaviour and physiology. These rhythms are underpinned by circadian clocks that run throughout the body, and act within each tissue to orchestrate many organ functions and rhythmic activities (e.g.
  Vitamin D and immunometabolism
  Prof M Hewison, Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Vitamin D has potent anti-inflammatory and antibacterial immune effects.
  Development of novel artificial intelligence algorithms for network wide metabolic flux analysis with stable isotope tracers
  Dr C Ludwig, Dr S He
Applications accepted all year round

Funding Type

PhD Type

The efficient function of the metabolic network in eukaryotic cells relies on its separation into a number of closely-linked but metabolically distinct compartments.
  Using CRISPR genome editing to determine the effects of obesity and hypertension associated polymorphisms
  Dr A MacKenzie, Prof M Delibegovic
Applications accepted all year round

Funding Type

PhD Type

Introduction. There is now little doubt that morbid conditions such as obesity, cardiovascular disease and diabetes are mechanistically linked.
  Adipose tissue remodelling in obesity and type 2 diabetes
  Dr K K Y Cheng
Applications accepted all year round

Funding Type

PhD Type

Background. Due to the changes in lifestyle and environment, the incidence of obesity has rapidly increased over the last two decades.
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  Adipose tissue functional responses to nutritional stress
  Dr K Manolopoulos, Prof D Calebiro
Applications accepted all year round

Funding Type

PhD Type

Obesity is the leading cause of insulin resistance and type 2 diabetes. Adipose tissue dysfunction has been proposed as being central in the pathophysiology of obesity-related complications.
  Identification of novel regulators of pancreatic beta-cell identity
  Dr I Akerman
Application Deadline: 31 October 2019

Funding Type

PhD Type

Diabetes is the largest epidemic in human history that affects 1 in 12 adults worldwide. Due to our modern lifestyle, it is one of the few diseases where the incidence is set to rise dramatically, with projections putting 650 million people at risk by 2040.
  Investigating metabolic changes in neurodegeneration
  Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round

Funding Type

PhD Type

This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
  Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks
  Dr A Antonysunil
Applications accepted all year round

Funding Type

PhD Type

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children.
  Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials
  Dr V Liu, Dr L Swanton
Applications accepted all year round

Funding Type

PhD Type

Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function.
  Investigating the mechanisms contributing to placental dysfunction in pregnancies complicated by diabetes: role of the hexosamine biosynthetic pathway
  Prof M Westwood, Prof J Aplin, Dr J Myers
Applications accepted all year round

Funding Type

PhD Type

Maternal diabetes is a major risk factor for fetal overgrowth, which is associated with poor outcomes including stillbirth, neonatal morbidity and increased risk of diabetes in adulthood.
  Sex hormone actions in frailty and health during ageing
  Dr M Garratt
Applications accepted all year round

Funding Type

PhD Type

It is well established that testosterone and estrogens can influence ageing, with hormone administration improving physical function, muscle and bone strength in some cohorts of the elderly.
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