University Medical Center Groningen
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cell therapy PhD Projects, Programmes & Scholarships
We have 27 cell therapy PhD Projects, Programmes & Scholarships
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Beating mesenchymal stem cell senescence with materials that organise growth factors.
Mesenchymal stem cells (MSCs) from the adult bone marrow can differentiate into cells that support the regeneration of tissues such as bone cartilage, ligament and tendon. Read more
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BBSRC PhD Studentship in Digital Twin supported development of viral vector production processes
BBSRC PhD Studentship in Digital Twin supported development of viral vector production processes. Department of Biochemical Engineering, University College London in collaboration with Oxford Biomedica. Read more
Cardiovascular effects of combination therapy with VEGF inhibitors and immune checkpoint inhibitors in cancer treatment
The success in cancer therapy observed in the past two decades is tightly associated with the introduction of new therapeutic strategies, which include combination therapies. Read more
Stochastic modelling and inference for live-cell gene expression data to unravel the mechanisms of stem cell differentiation
Research Group:
Statistical Medicine and Molecular Biology
This project will develop statistical methodology and computational algorithms to estimate model parameters using live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more
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Modelling cargo loaded macrophage trafficking across liver endothelium: a new approach to drug delivery in liver cancer
Cases of primary liver cancer, also known as hepatocellular cancer (HCC) are rising rapidly in the UK and new therapies are urgently needed. Read more
ABM CDT The mechanisms of portable negative pressure wound therapy on wounds
Wounds are a major unmet healthcare burden that impact on millions of patients per year. From those undergoing simple surgeries to complex ulcers of the lower limbs, a common form of therapy is the use of negative pressure wound therapy. Read more
PRIORITIZING DRUG COMBINATIONS IN LEUKEMIA BASED ON ANALYSIS OF TARGETTED THERAPY IN VIVO
The inhibition of BCR-associated kinases by so-called B cell receptor signalling inhibitors in B cell leukemia and lymphomas is a potent therapeutic strategy, and several BTK and PI3K kinase inhibitors are available for clinical use (Ondrisova and Mraz, 2020). Read more
Exploring G Protein-Coupled Receptor signaling and dietary oils for treatment of beta cell dysfunction, insulin resistance and inflammation in type 2 diabetes
Research Group:
Biomedical Sciences
The prevalence of type 2 diabetes has risen dramatically during recent decades and there is an urgent need to develop new approaches that provide a combination of benefits, with fewer side effects. Read more
Understanding the chromosome 11 CRC risk locus genes and the role they play in intestinal homeostasis
The 11q23 locus, was identified by GWAS as a CRC risk locus (Tenesa*, Farrington* et al, 2008). The three genes within the locus – C11orf53, COLCA1 and COLCA2 – have also been shown to be eQTLs (expression quantitative trait loci) for regional SNPs in human colonic normal epithelium (Vaughan-Shaw et al, 2021). Read more
THE PRECISION OF NEW THERAPIES FOR INTRAOPERATIVE BRAIN CANCER SURGERY
The clinical need. Glioblastoma is the most aggressive primary brain tumour and the cancer with the most years of potential life lost in adults. Read more
Developing functionalised electrospun scaffolds to exploit neural–stromal interactions in wound healing (Industry Project)
The ABM CDT is a partnership between The Universities of Manchester and Sheffield. ALL APPLICATIONS should however, be submitted via the Manchester application system only. Read more
Developing functionalised electrospun scaffolds to exploit neural–stromal interactions in wound healing (Industry Project)
The ABM CDT is a partnership between The Universities of Manchester and Sheffield. ALL APPLICATIONS should however, be submitted via the Manchester application system only. Read more
Characterization of the protective and therapeutic role of photobiomodulation on 3D oral mucosal and salivary gland models subjected to radiotherapy
Radiotherapy (RT) is a common standard therapy used for locally advanced head and neck malignant tumours. The radiation triggers the production of free radicals that can cause direct damage to the DNA structure of malignant cells. Read more
Understanding the role of cholesterol in the survival and treatment resistance of glioblastoma and its feasibility as a druggable target to improve treatment prognosis
A fully funded 3-year PhD studentship is available to work with Dr Natividad Gomez-Roman at the University of Strathclyde in Glasgow, UK. Read more
15 fully-funded MSCA PhD positions in Advanced Glaucoma Research in the Netherlands, Norway, Germany or France!
Glaucoma is an age-related neurodegenerative eye disease. Despite efforts of the early detection and treatment of glaucoma, ~15% of all patients in the EU still become bilaterally blind. Read more
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