Respiratory viral infections are the most prevalent illnesses in humans. In addition to their immediate health effects, these infections can result in long-term lung conditions like pulmonary fibrosis and worsen existing chronic lung diseases. Read more
Academic Supervisor. Teresa Rayon. Industrial Partner. bit.bio. The Babraham Research Campus (BRC) is pleased to announce a number of studentships from its BBSRC Collaborative Training Partnership (CTP) Award to start in October 2025. Read more
Schistosoma mansoni is one of three major schistosome species that infect over 240 million people across 70 developing countries, with an additional 0.6 billion at risk of infection. Read more
Project Summary. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, for which there is currently no effective treatment. Read more
Human cerebral organoids are generated from stem cells, forming a brain-like tissue in the laboratory dish. When grown from patient-specific induced pluripotent stem cells (iPSC), they offer an in vitro model for mechanistic studies of brain disorders and for personalised drug screening. Read more
The choroid plexus (ChP) is a vital yet understudied brain structure, responsible for secreting cerebrospinal fluid (CSF) and forming the blood-CSF barrier (B-CSF-B). Read more
Project Overview. The Wilkinson research group focuses on the biology and translational applications of blood-forming haematopoietic stem cells (HSCs). Read more
Project Overview. Functional interrogation of human gastrulation in bioprinted embryo models. How do complex body patterns emerge in the early embryo? The first signs of the human body axis can be traced back to the second week of gestation. Read more
Mitochondrial diseases are caused by defects in genes required for energy production and oxidative phosphorylation (OxPhos). We find it intriguing that some patients with mitochondrial disease present late in life, with very tissue-specific phenotypes. Read more
Project Overview. Some organisms, such as salamanders, retain a remarkable capacity for regeneration in various organs, which occurs through the process of epimorphic regeneration. Read more
This full-time DPhil post at the Botnar Institute will use cutting edge laboratory and computational methods to interrogate the mechanisms underlying failed repair following scaphoid fracture. Read more
About the project. Heart disease is a critical health burden and leading cause of mortality worldwide. To understand disease mechanisms and develop future treatments for heart disease, we have developed a human cardiac organoid platform derived from pluripotent stem cells. Read more
Project Overview. Whipworms infect hundreds of millions of people and cause trichuriasis, a major neglected disease. These large metazoan parasites inhabit a multi-intracellular niche within their host gut lining, where they can remain for years. Read more
Project Overview. We have pioneered the use of induced pluripotent stem cells from patients with genetically mediated aortic aneurysms (such as Marfan and Loeys-Dietz syndromes) to set up ‘disease-in-a-dish’ in vitro models (PMIDs. Read more
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