Metastasis in breast cancer reduces five-year survival rates in the UK from 99% to 15%[1]. One of the most common sites for tumour metastasis is bone, affecting approximately 70% of patients with over 24,000 in the UK alone[1]. Read more
Application deadline - midday (GMT) Friday 10 January 2025. Additional supervisor. Dr Alex Thompson, University of Nottingham. Over 90,000 people receive stem cell transplants every year worldwide for illnesses such as blood cancer. Read more
Respiratory viral infections are the most prevalent illnesses in humans. In addition to their immediate health effects, these infections can result in long-term lung conditions like pulmonary fibrosis and worsen existing chronic lung diseases. Read more
During nervous system development, neural stem cells must balance decisions between proliferation to allow growth, and differentiation, to generate functional neurons. Read more
Terrestrial life ultimately depends on plant meristems -small populations of undifferentiated stem cells that produce all major plant organs such as leaves and flowers that are critical for agriculture and food security. Read more
About. The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales. Read more
In mammals, the formation of sperm and eggs is crucial for initiating a new life cycle. The first step in this developmental process is the specification of primordial germ cells (PGCs) in the early post-implantation embryo. Read more
The use of dental implants has become a common treatment for the replacement of missing or damaged teeth. It is estimated that 10% of the world’s population will need a dental implant in their lifetime. Read more
We study how tens of thousands of neural crest cells, each belonging to a limited set of discrete neural crest stem cell populations are creating complex 3D structures such as teeth, craniofacial structures, heads and tongues. Read more
Gene regulation is at the heart of many biological processes, including the processes by which embryonic stem cells differentiate to become adult tissues. Read more
Background. The discovery of induced-pluripotent stem cells (iPSCs) has dramatically revolutionised our understanding of stem cell biology. Recently, 3D cultures have emerged as a significant advancement in regenerative medicine. Read more
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